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Telisotuzumab vedotin
go.drugbank.com/drugs/DB15104ApprovedInvestigational[L53193] Telizotuzumab vedotin-tllv was approved by the US FDA in May 2025 for previously treated advanced NSCLC patients with high c-Met protein overexpression,[L53158,L53183] becoming the first treatment … [L53158] The c-Met protein is found to be overexpressed in approximately 25% of advanced EGFR wild type, non-squamous NSCLC patients and is associated with poor prognosis and limited treatment options.
Categories: Amino Acids, Peptides, and ProteinsVoxilaprevir
go.drugbank.com/drugs/DB12026ApprovedInvestigationalBy inhibiting viral protease NS3/4A, voxilaprevir therefore prevents viral replication and function. … Voxilaprevir exerts its antiviral action by reversibly binding and inhibiting the NS3/4A serine protease of Hepatitis C Virus (HCV) [FDA Label].
Mixtures: VOSEVI FILM-COATED TABLETS 400MG/100MG/100MGCategories: Amino Acids, Peptides, and Proteins, sofosbuvir, velpatasvir and voxilaprevirTechnetium Tc-99m sulfur colloid
go.drugbank.com/drugs/DB09397Approved(intraperitoneal injection), is taken up by reticulocytes (intravenous injection), or enters the gastroesphageal tract (oral administration). … studies of esophageal transit and gastroesophageal reflux.
Categories: Indicators and Reagents, Hepatic and Reticulo Endothelial SystemHexachlorophene
go.drugbank.com/drugs/DB00756ApprovedWithdrawnIt is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797) … A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms.
Categories: Phenol and Derivatives, Antiseptics and DisinfectantsAlmasilate
go.drugbank.com/drugs/DB13595ApprovedIt is a crystalline polyhydrate of aluminium/magnesium silicate and mediates its buffering activity by binding hydrogen ions within the polymer. … Almasilate is a buffering antacid that has been used in peptic ulcers and dyspepsia.
Categories: Alimentary Tract and Metabolism, Aluminum and magnesium containing antacidsParethoxycaine
go.drugbank.com/drugs/DB19380ApprovedWithdrawnParethoxycaine is a local anesthetic that was previously approved in the US.
Deep Vein Thrombosis
go.drugbank.com/conditions/DBCOND0029964Drugs: Apixaban · Certoparin · Dabigatran etexilate · Dalteparin · Dermatan sulfate · Desirudin +9 moreSynonyms: Acute embolism and thrombosis of unspecified deep veins of lower extremity, (Deep vein phlebitis and thrombophlebitis of the leg) or (deep vein thrombosis)Lipegfilgrastim
go.drugbank.com/drugs/DB13200ApprovedNeutropenia and febrile neutropenia (FN) are frequent and potentially fatal complications that occur from myelosuppressive anticancer treatments [A32665]. … PEG moiety protects the active molecule from enzyme degradation, which allows longer half-life of drug and less frequent dosing-schedule in addition to acceptable safety and efficacy profile [A32665].
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsLodoxamide
go.drugbank.com/drugs/DB06794ApprovedAlthough less effective than topical steroids at decreasing inflammation, mast-cell stabilizers offer another treatment option and exhibit minimal adverse effects. … Lodoxamide is marketed under the brand name Alomide by Alcon.
Categories: Decongestants and Antiallergics, Amino Acids, Peptides, and ProteinsFluticasone furoate
go.drugbank.com/drugs/DB08906ApprovedInvestigationalFluticasone furoate is a synthetic glucocorticoid available as an inhaler and nasal spray for various inflammatory indications[FDA Label][F4364]. Fluticasone furoate was first approved in 2007[L5965].
Mixtures: Fluticasone Furoate and Vilanterol, Fluticasone Furoate and VilanterolCategories: vilanterol and fluticasone furoate, vilanterol, umeclidinium bromide and fluticasone furoate