Search

Displaying results 2761 - 2770 of 10000 in total
  1. Target

    Disintegrin and metalloproteinase domain-containing protein 10

    go.drugbank.com/bio_entities/BE0002404
    TargetHumans

    Transmembrane metalloprotease which mediates the ectodomain shedding of a myriad of transmembrane proteins, including adhesion proteins, growth factor precursors and cytokines being essential for development and tissue homeostasis (PubMe...

    Synonyms: KUZ
  2. Drug

    Gliquidone

    go.drugbank.com/drugs/DB01251
    Approved

    Gliquidone is a sulfonylurea drug used to treat diabetes mellitus type 2. It is an ATP-dependent K+ (KATP) channel blocker. … This block causes a depolarization which leads to activation of voltage-dependent Ca channels and Ca2+ influx, and eventually increases insulin release.

    International brands: Ka Rui Lin
  3. Drug

    Melphalan flufenamide

    go.drugbank.com/drugs/DB16627
    ApprovedWithdrawn

    Melphalan flufenamide, also known as melflufen or J1, is a prodrug of [melphalan]. … [A230123] The increased potency makes melphalan flufenamide a treatment option for patients with relapsed or refractory multiple myeloma who have attempted at least 4 lines of therapy already.

  4. Drug

    Phenylacetic acid

    go.drugbank.com/drugs/DB09269
    Approved

    Phenylacetic acid is an organic compound containing a phenyl functional group and a carboxylic acid functional group. It is a white solid with a disagreeable odor. … Because it is used in the illicit production of phenylacetone (used in the manufacture of substituted amphetamines), it is subject to controls in countries including the United States and China.

    Synonyms: ANTINEOPLASTON AS 2-1 COMPONENT PHENYLACETIC ACID
  5. Drug

    Eplontersen

    go.drugbank.com/drugs/DB16199
    ApprovedInvestigational

    [A262985] As eplontersen targets both the WT and mutant TTR, it poses tremendous promises as a treatment. … It was previously investigated as a potential treatment for hereditary transthyretin-mediated amyloidosis.

  6. Drug

    Fosdenopterin

    go.drugbank.com/drugs/DB16628
    Approved

    Molybdenum cofactor deficiency (MoCD) is an exceptionally rare autosomal recessive disorder resulting in a deficiency of three molybdenum-dependent enzymes: sulfite oxidase (SOX), xanthine dehydrogenase … [A230088] Signs and symptoms begin shortly after birth and are caused by a build-up of toxic sulfites resulting from a lack of SOX activity.

  7. Drug

    Pork collagen

    go.drugbank.com/drugs/DB14100
    Approved

    It serves as an alternative repair treatment for patients with inadequate response to pre-existing surgical methods. … Pork Collagen is used within MACI® (autologous cultured chondrocytes on porcine collagen membrane) as an autologous cellularized scaffold product indicated for the repair of single or multiple symptomatic

  8. Drug

    Ergosterol

    go.drugbank.com/drugs/DB04038
    ApprovedWithdrawn

    A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS break a bond to result

    Categories: Diet, Food, and Nutrition
  9. Drug

    Dexamethasone metasulfobenzoate

    go.drugbank.com/drugs/DB14703
    Approved

    Mixtures: Sofracort Eye/ear Drops, Sofracort Sterile Ear/eye Drops
  10. Drug

    Tinidazole

    go.drugbank.com/drugs/DB00911
    ApprovedInvestigational

    A nitroimidazole antitrichomonal agent effective against _Trichomonas vaginalis_, _Entamoeba histolytica_, and _Giardia lamblia_ infections.

    Mixtures: GYNOMAX L VAJINAL OVUL, 7 ADET, GYNOMAX 100 MG/150 MG VAJINAL OVUL, 7 ADETCategories: combinations of imidazole derivatives