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Agkistrodon piscivorus antivenin
go.drugbank.com/drugs/DB13894ApprovedThe cottonmouth habitat range extends from southeastern Virginia (near the junction of the Appomattox and James rivers) to southern Florida, west to central Texas, Oklahoma, Arkansas, Missouri, and southeastern … In North America, members of the family Crotalidae belong to three genera: the rattlesnakes (Crotalus and Sistrurus spp.) and the copperheads and cottonmouth water moccasins (Agkistrodon spp.)
P2X purinoceptor 3
go.drugbank.com/bio_entities/BE0009818TargetHumansExtracellular ATP-activated non-selective cation channel (PubMed:10440098, PubMed:27626375, PubMed:29674445, PubMed:31232692). Plays particularly important role in sensory neurons where its activation is critical for gustatory, nocicepti...
Synonyms: ATP receptor, Purinergic receptorP2X purinoceptor 2
go.drugbank.com/bio_entities/BE0009820TargetHumansATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium (PubMed:10570044, PubMed:31636190). Activation by extracellular ATP induces a variety of cellular responses, such as excitatory postsynaptic r...
Synonyms: ATP receptor, Purinergic receptorMelatonin
go.drugbank.com/drugs/DB01065ApprovedInvestigationalNutraceuticalVet approvedThe pineal gland is small endocrine gland, about the size of a rice grain and shaped like a pine cone (hence the name), that is located in the center of the brain (rostro-dorsal to the superior colliculus … The secretion of melatonin increases in darkness and decreases during exposure to light, thereby regulating the circadian rhythms of several biological functions, including the sleep-wake cycle.
Categories: Melatonin Receptor AgonistsInternational brands: Mela-TElbasvir
go.drugbank.com/drugs/DB11574Approved[synthesis] The barrier to the development of resistance to NS5A inhibitors is lower than that of NS5B inhibitors, another class of DAAs. … of SARS-CoV-2, the human coronavirus responsible for the COVID-19 pandemic.
Quizartinib
go.drugbank.com/drugs/DB12874ApprovedInvestigational[A260651] Therefore, quizartinib is proven to be a beneficial addition to the current AML treatment regimen, although serious side effects such as QT prolongation necessitates further research to optimize … [A260641] Quizartinib was approved by the FDA in July 2023 and developed under the brand name VANFLYTA by Daiichi Sankyo.
Hydroxyethyl cellulose
go.drugbank.com/drugs/DB11602ApprovedIt is often used as an ingredient in ophthalmic pharmaceutical preparations such as artificial tear solutions and adjunct agent in topical drug formulations to facilitate the delivery of drugs with hydrophobic … It is used as a key ingredient in many household cleaning products, lubricants and cosmetics due to its non-ionic and water-soluble nature.
Dabrafenib
go.drugbank.com/drugs/DB08912ApprovedInvestigationalIt was approved on May 29, 2013, for the treatment of melanoma with V600E or V6000K mutation.[L41955] It was also used for metastatic non-small cell lung cancer with the same mutation. … Dabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK pathway.
Oprelvekin
go.drugbank.com/drugs/DB00038ApprovedInvestigationalWithdrawnWith a molecular mass of approximately 19,000 daltons, the non-glycosylated protein is 177 amino acids in length in comparison to the natural IL-11, which is 178 amino acid long. … nadirs and accelerated platelet recoveries compared to controls.
Atogepant
go.drugbank.com/drugs/DB16098ApprovedInvestigationalto other preventative therapies. … It was developed by AbbVie and received FDA approval under the brand name Qulipta in September 2021.
Categories: Calcitonin Gene-Related Peptide Receptor Antagonists