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Diethylcarbamazine
go.drugbank.com/drugs/DB00711ApprovedInvestigationalVet approvedWithdrawnAn anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.
Regorafenib
go.drugbank.com/drugs/DB08896ApprovedInvestigationalApproved use of Regorafenib was expanded to treat Hepatocellular Carcinoma in April 2017. … It is used for the treatment of metastatic colorectal cancer, advanced gastrointestinal stromal tumours, and hepatocellular carcinoma. FDA approved on September 27, 2012.
Tetraferric tricitrate decahydrate
go.drugbank.com/drugs/DB14520ApprovedInvestigationalTetraferric tricitrate decahydrate is an iron containing phosphate binder used to treat hyperphosphatemia and iron deficiency anemia in adults with chronic kidney disease.
Nirogacestat
go.drugbank.com/drugs/DB12005ApprovedInvestigational3 DeFi trial, where a confirmed objective response rate was observed to be 41% compared to 8% with the placebo. … and thus impede the growth of desmoid tumors.
Thiohexam
go.drugbank.com/drugs/DB14200ApprovedSensitivity to Thiohexam may be identified with a clinical patch test.
Bromodiphenhydramine
go.drugbank.com/drugs/DB01237ApprovedBromodiphenhydramine is used in the control of cutaneous allergies. Ethanolamine antihistamines produce marked sedation in most patients.
Clonidine
go.drugbank.com/drugs/DB00575ApprovedInvestigational[A180559] This activity is useful for the treatment of hypertension, severe pain, and ADHD.[L7237,L54536,L7240,L7243,L7246] Clonidine was granted FDA approval on 3 September 1974.[L7237]
Black cohosh
go.drugbank.com/drugs/DB13975ApprovedEuropean settlers were said to use black cohosh as a tonic to support female reproductive health. … [A32543] The American College of Obstetrics and Gynecology guidelines on the use of botanicals, such as black cohosh, for the management of menopausal symptoms the use of for up to six months, especially
Ethionamide
go.drugbank.com/drugs/DB00609ApprovedInvestigationalWithdrawnIt also may be used for treatment of leprosy. (From Smith and Reynard, Textbook of Pharmacology, 1992, p868)
Chlormadinone acetate
go.drugbank.com/drugs/DB15903ApprovedWithdrawnHowever, the use of these drugs was associated with the development of mammary tumors in dogs. In 1972, the FDA withdrew its approval for the use of chlormadinone acetate in all products. … [L43942,L42975] Chlormadinone acetate continues to be used in other countries due to its high contraceptive efficacy and tolerability.[A254422,L33974]
Mixtures: LUTORAL-E