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Pizotifen
go.drugbank.com/drugs/DB06153ApprovedSandomigran is available in a number of countries but is not approved by the FDA nor EMA. … Pizotifen hydrochloride is an active ingredient in Sandomigran, which is used for the prophylactic management of migraines.
Ergoloid mesylate
go.drugbank.com/drugs/DB01049Approved[L2639]Later in 1991, the mixture of ergoloid mesylates was retaken by Sun Pharmaceutical Industries and approved by the FDA. … Ergoloid Mesylate is an equiproportional preparation of three different ergotamantriones: dihydroergocornine, dihydroergocristine, and dihydroergocryptine.
Products: SEGOL 1 MG/ML DAMLA, ÇÖZELTİ, 50 MLDiphenylguanidine
go.drugbank.com/drugs/DB14191ApprovedDiphenylguanidine is a complexing agent used in the detection of metals and organic bases and used as an accelerator in the vulcanization of rubber. It is found in some rubber products. … It is also a dermatological sensitizer and allergen. Sensitivity to diphenylguanidine may be identified with a clinical patch test.
SP1049C
go.drugbank.com/drugs/DB04978ExperimentalPreliminary data, in its first clinically tested indication, shows that SP1049C is active in Stage IV non-resectable adenocarcinoma of the esophagus. … [A260416] It is designed to overcome drug resistance in a number of cancers. It has successfully completed Phase 1 trials. Phase 2 results are currently under final review.
Categories: Compounds used in a research, industrial, or household settingSynonyms: doxorubicin with pluronics F-127 and L-61, Doxorubicin HCl with pluronic L-61 and pluronic F-127Duvelisib
go.drugbank.com/drugs/DB11952ApprovedInvestigationalAll the work around duvelisib showed that this agent is a potent inhibitor of both forms.[A39025] Duvelisib was developed by Verastem, Inc and FDA approved on September 24, 2018.[L4585] … Duvelisib, also known as IPI-145 and INK-1197, is a small-molecule inhibitor of phosphoinositide-3 kinases that was designed initially to prove that simultaneous inhibition of the isoforms delta and gamma
Sonrotoclax
go.drugbank.com/drugs/DB18753ApprovedInvestigationalSonrotoclax is a selective, potent, small-molecule inhibitor of BCL-2, an antiapoptotic protein overexpressed in B-cell malignancies. … It is the first BCL-2 inhibitor approved for MCL and the second oncology-approved BCL-2 inhibitor overall, following venetoclax.
Synonyms: N-[4-({[(1r,4r)-4-hydroxy-4-methylcyclohexyl]methyl}amino)-3- nitrobenzene-1-sulfonyl]-4-(2-{(2S)-2-[2-(propan-2-yl)phenyl]pyrrolidin- 1-yl}-7-azaspiro[3.5]nonan-7-yl)-2-[(1H-pyrrolo[2,3-b]pyridin-5- ylDanazol
go.drugbank.com/drugs/DB01406ApprovedInvestigationalIt possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.
Iodine povacrylex
go.drugbank.com/drugs/DB09537ApprovedIt is a broad spectrum antiseptic and can provide almost 99.9% antiseptic conditions. It is intended for local use only. … Iodine povacrylex (DuraPrep) is a surgical solution, film-forming iodophor complex that provides fast acting, persistent, broad-spectrum antimicrobial activity.
Uric acid
go.drugbank.com/drugs/DB08844InvestigationalAs a therapeutic agent, it is known that uric acid is increased in response to oxidative stress, and as such, uric acid acts as an antioxidant. … In one country, Spain, uric acid is an investigational drug in a phase 3 trial studying its effects as an adjunct to alteplase in acute ischemic stroke.
Categories: Compounds used in a research, industrial, or household settingLodoxamide
go.drugbank.com/drugs/DB06794ApprovedLodoxamide is marketed under the brand name Alomide by Alcon. … Lodoxamide is a mast-cell stabilizer for topical administration into the eye.
Products: THILOMIDE GÖZ DAMLASI, 5 ML, ALOMİDE % 0.1 GÖZ DAMLASI, ÇÖZELTİ, 5 ML