Diphenylguanidine is a complexing agent used in the detection of metals and organic bases and used as an accelerator in the vulcanization of rubber. It is found in some rubber... It is also a dermatological sensitizer and allergen.
- Mechanism
- Curator reviewed
Pharmacologically active on High mobility group protein B1
- Primary indication
- Diphenylguanidine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age and older.Curator reviewed
- Formula / weight
- C13H13N3 · 211.268 g/mol (avg)
- First approval
- United States, 2012
- Also known as
- 1,3-diphenylguanidine · DPG vulcanizer · Melaniline · N,N'-diphenylguanidine · s-Diphenylguanidine
Resolves to
Clinical / RWD
Structure
InChIKey
OWRCNXZUPFZXOS-UHFFFAOYSA-NSMILESN=C(NC1=CC=CC=C1)NC1=CC=CC=C1Targets
What you can answer from here — as of August 30, 2026
Which drugs share a target with Diphenylguanidine, and which of those have an active Phase 3 trial?
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