Search

Displaying results 2791 - 2800 of 2828 in total
  1. Drug

    Cloprednol

    go.drugbank.com/drugs/DB13843
    Investigational

    Cloprednol is a synthetic glucocorticoid that has been investigated for use in the treatment of asthma.

    Categories: Sex Hormones and Insulins
  2. Drug

    Terguride

    go.drugbank.com/drugs/DB13399
    Experimental

    Categories: Genito Urinary System and Sex Hormones
  3. Target

    Sodium/Potassium Transporting ATPase

    go.drugbank.com/bio_entities/BE0010055
    TargetTransporterHumans

    Transports 3 Na(+) ions out of the cell and 2 K(+) ions into the cell for each ATP hydrolyze (PubMed:16861705). … May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase

    Synonyms: FXYD domain-containing ion transport regulator 2
  4. Drug

    Dabrafenib

    go.drugbank.com/drugs/DB08912
    ApprovedInvestigational

    Dabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK pathway. It was approved on May 29, 2013, for the treatment of melanoma with V600E or V6000K mutation. It was also used for metastatic n...

    Categories: Organic Anion Transporter 1 Inhibitors
  5. Drug

    Nivolumab

    go.drugbank.com/drugs/DB09035
    ApprovedInvestigational

    Nivolumab is a fully human IgG4 antibody targeting the immune checkpoint programmed death receptor-1 (PD-1). This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region with the mutation S228P for addition...

  6. Drug

    Cortivazol

    go.drugbank.com/drugs/DB13003
    Investigational

    Cortivazol is under investigation in clinical trial NCT00804895 (Cluster Headache Cortivazol Injection (CHCI)).

    Categories: Sex Hormones and Insulins
  7. Drug

    Flunoxaprofen

    go.drugbank.com/drugs/DB13317
    Experimental

    Categories: Genito Urinary System and Sex Hormones
  8. Drug

    Vemurafenib

    go.drugbank.com/drugs/DB08881
    ApprovedInvestigational

    Vemurafenib is a competitive kinase inhibitor with activity against BRAF kinase with mutations like V600E. It exerts its function by binding to the ATP-binding domain of the mutant BRAF. Vemurafenib was co-developed by Roche and Plexxiko...

    Categories: Genito Urinary System and Sex Hormones
  9. Drug

    Triamcinolone

    go.drugbank.com/drugs/DB00620
    ApprovedInvestigationalVet approved

    [L8243] In October 2021, a suspension of triamcinolone acetonide was approved for suprachoroidal injection - the first suprachoroidal injection to receive FDA approval[L38973] - for the treatment of patients

    Categories: Sex Hormones and Insulins
  10. Drug

    Prednisolone

    go.drugbank.com/drugs/DB00860
    ApprovedInvestigationalVet approved

    Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.

    Categories: Sex Hormones and Insulins