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Enlicitide
go.drugbank.com/drugs/DB22580ApprovedInvestigationalAcross two 52-week placebo-controlled trials, enlicitide 20 mg once daily reduced LDL-C at Week 24 by 56% relative to placebo in patients with hypercholesterolemia at established or increased ASCVD risk … It is formulated as enlicitide decanoate alongside the permeation enhancer sodium caprate, which facilitates absorption of the peptide across the gastrointestinal tract, though oral bioavailability remains
Cinaciguat
go.drugbank.com/drugs/DB16126InvestigationalCinaciguat is under investigation in clinical trial NCT01067859 (A Phase Iib Study to Investigate the Efficacy and Tolerability of Lower Doses Cinaciguat (25 ΜG/h, 10 ΜG/h) Given Intravenously to Patients
3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase
go.drugbank.com/bio_entities/BE0001554TargetStreptomyces exfoliatusPolypeptides: 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenaseMitogen-activated protein kinase kinase kinase 20
go.drugbank.com/bio_entities/BE0005595TargetHumansStress-activated component of a protein kinase signal transduction cascade that promotes programmed cell death in response to various stress, such as ribosomal stress, osmotic shock and ionizing radiation (PubMed:10924358, PubMed:1183624...
Polypeptides: Mitogen-activated protein kinase kinase kinase 20Mepenzolate
go.drugbank.com/drugs/DB04843ApprovedWithdrawnIt has not been shown to be effective in contributing to the healing of peptic ulcer, decreasing the rate of recurrence, or preventing complications. … Pharmacologically, it is a post-ganglionic parasympathetic inhibitor.
Beta-lactamase OXA-10
go.drugbank.com/bio_entities/BE0001274TargetEnzymePseudomonas aeruginosaHydrolyzes both carbenicillin and oxacillin.
Polypeptides: Beta-lactamase OXA-10Medrogestone
go.drugbank.com/drugs/DB09124ApprovedWithdrawn[L1118] It was never approved by the FDA. … It was conceived as an alternative for an orally effective contraceptive option.[A31526] It was developed by Ayerst, approved in Canada in 1969 and its current status is cancelled post-marketing.
Mixtures: PRESOMEN 28 COMP 0.3/5MG, PRESOMEN 28 COMP 0.3/5MGProducts: Colprone Tab 5mgCytosolic 10-formyltetrahydrofolate dehydrogenase
go.drugbank.com/bio_entities/BE0000933TargetHumansCytosolic 10-formyltetrahydrofolate dehydrogenase that catalyzes the NADP(+)-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide (PubMed:19933275, PubMed:21238436).
Polypeptides: Cytosolic 10-formyltetrahydrofolate dehydrogenaseSynonyms: 10-FTHFDHBone morphogenetic protein 10
go.drugbank.com/bio_entities/BE0010910TargetHumansRequired for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors s...
Polypeptides: Bone morphogenetic protein 10Synonyms: BMP-10