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Isopropamide
go.drugbank.com/drugs/DB01625ApprovedVet approvedWithdrawnIsopropamide iodide is a long-acting quaternary anticholinergic drug. It is used in the treatment of peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility.
Categories: Drugs for Functional Gastrointestinal DisordersFenoxaprop-ethyl
go.drugbank.com/drugs/DB05252ExperimentalFenoxaprop-ethyl (organic nitrate combined with L-arginine), is an oral proprietary nitrate therapeutic shown to induce coronary vasodilation while overcoming the significant problem of drug tolerance.
Cytisine
go.drugbank.com/drugs/DB09028InvestigationalRecent studies have shown it to be a more effective and significantly more affordable smoking cessation treatment than nicotine replacement therapy. … Recent Phase III clinical trials using Tabex (a brand of Cytisine marketed by Sopharma AD) have shown similar efficacy to varenicline, but at a fraction of the cost.
Isoeugenol
go.drugbank.com/drugs/DB14188ApprovedAllergic reactivity to Isoeugenol may be identified with a patch test. … Isoeugenol is a commonly used fragrance added to many commercially available products, and occurs naturally in the essential oils of plants such as ylang-ylang.
Synthetic Conjugated Estrogens, A
go.drugbank.com/drugs/DB09317ApprovedThis shift in hormone production is largely responsible for many of the symptoms experienced during and after menopause and includes hot flashes and other vasomotor symptoms, painful intercourse, vaginal … This blend of nine estrogen derivatives are plant-derived forms of endogenous estrogens and contain many of the same compounds as the Conjugated Equine Estrogens (CEEs), although they are not considered
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesBerberine
go.drugbank.com/drugs/DB04115ApprovedInvestigationalWithdrawnAn alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. … It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 InhibitorsCerivastatin
go.drugbank.com/drugs/DB00439ApprovedWithdrawnOn August 8, 2001 the U.S. Food and Drug Administration (FDA) announced that Bayer Pharmaceutical Division voluntarily withdrew Baycol from the U.S. market, due to reports of fatal rhabdomyolysis, a severe adverse reaction from this chol...
Categories: Hypolipidemic Agents Indicated for Hyperlipidemia, P-glycoprotein substratesRosoxacin
go.drugbank.com/drugs/DB00817ApprovedRosoxacin is a quinolone derivative antibiotic for the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseMirvetuximab soravtansine
go.drugbank.com/drugs/DB12489ApprovedInvestigational[A254382] After an ADC/receptor complex is formed, mirvetuximab soravtansine-gynx is internalized, and DM4 is released inside the cell. … [L50306] In October 2024, it was approved in the EU for the same indication. [L52640]
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesCefdinir
go.drugbank.com/drugs/DB00535ApprovedInvestigationalIt has been proven to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and skin.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use