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Displaying results 2831 - 2840 of 10000 in total
  1. Drug

    Macitentan

    go.drugbank.com/drugs/DB08932
    ApprovedInvestigational

    A combination product (Opsynvi) comprising macitentan and [tadalafil] was approved in Canada in October 2021 for the treatment of PAH.[L39105] It was subsequently approved by the FDA in March 2024. … Macitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH).[L35890] It was first approved by the FDA in 2013.

    Mixtures: OPSYNVI® (MACITENTAN/TADALAFILO) 10MG/40 MG TABLETAS RECUBIERTASCategories: Heterocyclic Compounds, 1-Ring, macitentan and tadalafil
  2. Drug

    Minnelide

    go.drugbank.com/drugs/DB17309
    Investigational

    Synonyms: Trisoxireno(4b,5:6,7:8a,9)phenanthro(1,2-c)furan-1(3h)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-8b-methyl-6a-(1-methylethyl)-6-((phosphonooxy)methoxy)-, sodium salt (1:2), (3bs,4as,5ar,6r,6as,7as,7bs,, 14-o-phosphonooxymethyltriptolide disodium salt
  3. Drug

    Prazosin

    go.drugbank.com/drugs/DB00457
    ApprovedInvestigational

    [L5828] It belongs to the class of drugs known as alpha-1 antagonists. … Prazosin is a drug used to treat hypertension. Prazosin is marketed by _Pfizer_ and was initially approved by the FDA in 1988.

    Categories: Peripheral alpha-1 blockers, Adrenergic alpha-1 Receptor AntagonistsSynonyms: 2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline, 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine
  4. Drug

    Levodropropizine

    go.drugbank.com/drugs/DB12472
    Investigational

    Levodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine).

    Mixtures: PULMOTUS 30 MG+ 2 MG/5 ML ŞURUP, 150 ML, DROPOLEV ŞURUP ,150 MLCategories: Cough and Cold Preparations
  5. Drug

    Tretinoin

    go.drugbank.com/drugs/DB00755
    ApprovedInvestigationalNutraceutical

    [A257689] In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. … and differentiation.

    Synonyms: Tretin M, (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acidInternational brands: Stieva-A
  6. Drug

    Econazole

    go.drugbank.com/drugs/DB01127
    Approved

    A broad spectrum antimycotic with some action against Gram positive bacteria. It is used topically in dermatomycoses also orally and parenterally.

    Mixtures: Econazole Nitrate 1% / Niacinamide 4%, 071023 Econazole Nitrate 1% / Niacinamide 4%Categories: Heterocyclic Compounds, 1-Ring, 14-alpha Demethylase Inhibitors
  7. Drug

    Felbamate

    go.drugbank.com/drugs/DB00949
    Approved

    Alternatively, it is used to treat partial and generalized seizures associated with Lennox-Gastaut syndrome in children. It has a weak inhibitory effect on GABA receptor binding sites. … In particular, in the adult patient population, it can be employed to treat partial seizures (with and without generalization).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: Carbamic acid 3-carbamoyloxy-2-phenyl-propyl ester, 2-phenyl-1,3-propanediol dicarbamate
  8. Drug

    Alirocumab

    go.drugbank.com/drugs/DB09302
    ApprovedInvestigational

    diet and statin treatment. … The FDA approval was contingent on the completion of further clinical trials to better determine efficacy and safety. PCSK9 inhibition facilitates more LDL-C clearance from the blood.

    Categories: Amino Acids, Peptides, and Proteins, Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) InhibitorsProducts: PRALUENT 150 MG/ML SC ENJEKSIYONLUK ÇÖZELTI IÇEREN KULLANIMA HAZIR ENJEKTÖR,1 ADET, PRALUENT 150 MG/ML SC ENJEKSIYONLUK ÇÖZELTI IÇEREN KULLANIMA HAZIR KALEM,1 ADET
  9. Drug

    Nepafenac

    go.drugbank.com/drugs/DB06802
    ApprovedInvestigational

    Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop. It is used to treat pain and inflammation associated with cataract surgery.

    Categories: Selective Cyclooxygenase 2 Inhibitors (NSAIDs)Synonyms: 2-amino-3-benzoylbenzeneacetamide
  10. Drug

    Ziprasidone

    go.drugbank.com/drugs/DB00246
    ApprovedInvestigational

    [A180748] Although ziprasidone is classified as an atypical antipsychotic, it appears to have a lower incidence of metabolic adverse effects compared to other medications in the same class.[A190525] … Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior.

    Categories: Adrenergic alpha-1 Receptor Antagonists, Heterocyclic Compounds, 1-RingProducts: Zeldox 10 mg/ml Suspension zum Einnehmen, ZELDOX 20 MG KAPSUL, 56 ADET