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Displaying results 2841 - 2850 of 5451 in total
  1. Drug

    Alitretinoin

    go.drugbank.com/drugs/DB00523
    Approved

    It is used in the treatment of psoriasis; acne vulgaris; and several other skin diseases. It has also been approved for use in promyelocytic leukemia (leukemia, promyelocytic, acute).

    Products: Alitretan 10 mg Kapseln, Alitretan 30 mg Kapseln
  2. Drug

    Estrone

    go.drugbank.com/drugs/DB00655
    Approved

    It is produced in vivo from androstenedione or from testosterone via estradiol. … It is produced primarily in the ovaries, placenta, and in peripheral tissues (especially adipose tissue) through conversion of adrostenedione.

    Products: Oestrilin Creme Vaginale 1mg
  3. Drug

    Gadoxetic acid

    go.drugbank.com/drugs/DB08884
    ApprovedInvestigational

    Ethoxybenzyl diethylenetriaminepentaacetic acid is the moiety that chelates with a gadolinium ion and forms a stable complex with it to make up the drug.

  4. Drug

    Doxorubicin

    go.drugbank.com/drugs/DB00997
    ApprovedInvestigational

    [A257709] Although its detailed molecular mechanisms have yet to be understood, doxorubicin is generally thought to exert its effect through DNA intercalation, which eventually leads to DNA damage and

    Products: DOLNIX 2 MG /ML, DOXORUBICINA 10 MG
  5. Drug

    Girentuximab I-124

    go.drugbank.com/drugs/DB15025
    Investigational

    Girentuximab I-124 is under investigation in clinical trial NCT01762592 (REDECT 2: REnal Masses: Pivotal Trial to DEteCT Clear Cell Renal Cell Carcinoma With PET/CT).

  6. Drug

    Cocarboxylase

    go.drugbank.com/drugs/DB01987
    ApprovedInvestigational

    It is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.

  7. Drug

    Avanafil

    go.drugbank.com/drugs/DB06237
    Approved

    [L32113] It first received FDA approval on April 27, 2012,[L32058] with subsequent EMA approval in June 2013.[L32113] … In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both [sildenafil] and [vardenafil] but less selectivity than [tadalafil], suggesting a relatively

    Products: STENDRA 100 MG TABLET, 2 ADET, STENDRA 100 MG TABLET, 4 ADET
  8. Drug

    Sodium stibogluconate

    go.drugbank.com/drugs/DB05630
    ApprovedInvestigational

    It is also being investigated as an anti-tumor agent. … It belongs to the class of medicines known as the pentavalent antimonials. Sodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline).

  9. Drug

    Tetraethylammonium

    go.drugbank.com/drugs/DB08837
    Investigational

    Because of its inhibitory actions at the autonomic ganglia, tetraethylammonium was thought to be a potential therapeutic vasodilator but serious toxic effects were found. … Its mechanism of action is still being investigated, but it is known that tetraethylammonium blocks autonomic ganglia, calcium- and voltage- activated potassium channels, and nicotinic acetylcholine receptors

  10. Drug

    alpha-Amyl cinnamaldehyde

    go.drugbank.com/drugs/DB14175
    Approved

    It is used in allergenic testing.