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Rescinnamine
go.drugbank.com/drugs/DB01180ApprovedRescinnamine is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug. It is an alkaloid obtained from _Rauwolfia serpentina_ and other species of _Rauwolfia_.
Categories: Heterocyclic Compounds, 2-RingInternational brands: Tsuruselpi SProchlorperazine
go.drugbank.com/drugs/DB00433ApprovedInvestigationalVet approvedProchlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic drug that is used for the treatment of severe nausea and vomiting, as well as short-term management … Although newer antiemetic agents such as 5-HT3 antagonists are more heavily promoted, prochlorperazine is still widely used in nausea and vomiting.[L6640]
Synonyms: 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine, 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesBenzyl alcohol
go.drugbank.com/drugs/DB06770ApprovedInvestigationalMixtures: Itch-X, Itch XCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesRegadenoson
go.drugbank.com/drugs/DB06213ApprovedInvestigationalRegadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
Categories: Adenosine A receptor agonists, Heterocyclic Compounds, 1-RingProducts: Lexiscan(r) (regadenoson)Natural Killer Cell
go.drugbank.com/drugs/DB15721InvestigationalGenerally, the number of NK cells collected in the peripheral blood mononuclear cell (PBMC) is too low for sufficient potency, and ex vivo expansion is performed. … It is also possible to culture UCB CD34+ hematopoietic stem cells (HSCs) under stimulation of IL-2, IL-15, and stem cell factor (SCF) in a system to develop NK cells.
Guvacine
go.drugbank.com/drugs/DB08848ExperimentalGuvacine is a pyridine alkaloid found in the Areca nut (also known as the Betel nut). It is an experimental drug with no approved indication. … Currently it has been determined that guvacine is a specific GABA reuptake inhibitor with no significant affinity at GABA receptors.
Categories: Heterocyclic Compounds, 1-RingNitroxoline
go.drugbank.com/drugs/DB01422ExperimentalIt is a hydroxyquinoline derivative unrelated to other classes of drugs.[A179251] Nitroxoline is active against bacterial gyrases. … Nitroxoline is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections.
Synonyms: 5-Nitro-8-quinolinol, 5-Nitro-8-oxyquinolineCategories: Heterocyclic Compounds, 2-RingSitafloxacin
go.drugbank.com/drugs/DB13261InvestigationalCategories: Topoisomerase II Inhibitors, 4-QuinolonesTetraethylammonium
go.drugbank.com/drugs/DB08837InvestigationalThe most common use of tetraethylammonium presently is as a pharmacological research agent that blocks selective potassium channels. … The only marketed drug containing tetraethylammonium was a combination drug called Fosglutamina B6, but this drug has now been discontinued.
Categories: MATE 1 Substrates, MATE 2 SubstratesPhosphocreatine
go.drugbank.com/drugs/DB13191InvestigationalNutraceuticalIt is primarily found endogenously in the skeletal muscles of vertebrates where it serves a critical role as a rapidly acting energy buffer for muscle cell actions like contractions via its ability to … Phosphocreatine - or creatine phosphate - is the phosphorylated form of creatine.
Categories: Compounds used in a research, industrial, or household settingSynonyms: N-(N-phosphonoamido)sarcosine, Creatine-P