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Displaying results 281 - 290 of 10000 in total
  1. Drug

    Brinzolamide

    go.drugbank.com/drugs/DB01194
    Approved

    [A2051] Brinzolamide was approved by the FDA in 1998 as a standalone product and in 2013 as a combination product with brimonidine tartrate. … [A2049,A2051] Although systemic anti-carbonic anhydrase (CA) therapy has been used for almost 50 years with varying degrees of success, systemic administration results in an increase in incidences of adverse

    Mixtures: AZARGA 10 MG/ML + 5 MG/ML, BRİTİL-T 10 MG/ML + 5 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADETCategories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Sugammadex

    go.drugbank.com/drugs/DB06206
    ApprovedInvestigational

    Sugammadex (brand name Bridion) is marketed by Merck Sharp and Dohme, and was approved by the United States FDA on December 15, 2015. … Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery.

    Products: BRIDION 500 MG/5 ML IV ENJEKSIYONLUK COZELTI ICEREN 10 FLAKON, SUGRİNO 200 MG/2 ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 10 ADET
  3. Drug

    Amantadine

    go.drugbank.com/drugs/DB00915
    ApprovedInvestigational

    The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.

    Synonyms: 1-adamantanamine, 1-adamantylamineCategories: M2 Protein Inhibitors, Influenza A M2 Protein Inhibitor
  4. Drug

    Citalopram

    go.drugbank.com/drugs/DB00215
    ApprovedInvestigational

    [A261316] Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 years or older.[L5230] … It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.

    Mixtures: Sentralopram AM-10Products: Celexa 10 mg, CITALOPRAM-NEURAX 10 MG
  5. Drug

    Astemizole

    go.drugbank.com/drugs/DB00637
    ApprovedWithdrawn

    It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice.

    Synonyms: 1-(p-Fluorobenzyl)-2-((1-(2-(p-methoxyphenyl)ethyl)piperid-4-yl)amino)benzimidazole, 1-(p-Fluorobenzyl)-2-((1-(p-methoxyphenethyl)-4-piperidyl)amino)benzimidazoleProducts: ALMIZOL 10 MG TABLET, 10 ADET, ULKAMIZOL 10 MG TABLET, 10 ADET
  6. Drug

    Alendronic acid

    go.drugbank.com/drugs/DB00630
    ApprovedInvestigational

    It functions by preventing resorption of bone[FDA Label][A959].

    Synonyms: 4-amino-1-hydroxybutane-1,1-diphosphonic acid, (4-amino-1-hydroxybutylidene)bisphosphonic acidMixtures: BONYL 70 MG/2800 IU TABLET, 12 ADET, BONYL PLUS 70 MG/5600 IU TABLET, 12 ADET
  7. Drug

    Budesonide

    go.drugbank.com/drugs/DB01222
    ApprovedInvestigational

    [A188529,A188532] Budesonide was granted FDA approval on 14 February 1994.[L10598] It is also available in a combination product with [formoterol].[L10619]

    Mixtures: FORBUSOL 12+200 MG İNHALASYON İÇİN TOZ İÇEREN KAPSÜL, 60+60 ADET, FORBUSOL 12+400 MG İNHALASYON İÇİN TOZ İÇEREN KAPSÜL, 60+60 ADETProducts: CORTİMENT MMX 9 MG UZATILMIŞ SALIMLI TABLET, 10 ADET, BUNASE 1.0 MG RESPULES
  8. Drug

    Ephedrine

    go.drugbank.com/drugs/DB01364
    ApprovedInvestigational

    [L12972] Ephedrine and [phenylephrine] are still used to treat hypotension, but their use in other indications has decreased due to the development of more selective adrenergic agonists.

    Synonyms: (1R,2S)-1-Phenyl-1-hydroxy-2-methylaminopropane, L-erythro-2-(Methylamino)-1-phenylpropan-1-olMixtures: BROKSIN 6.66 MG/5 ML+100 MG/5 ML SURUP, 150 ML, ARTU 100 ML SURUP
  9. Drug

    Menadione

    go.drugbank.com/drugs/DB00170
    ApprovedNutraceutical

    A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.

    Mixtures: LIBAVIT-K 20 MG AMPUL, 5 ADETProducts: VITAMIN K 10 MG, VI-PLEX K 10 MG/2 ML AMPUL, 50 ADET
  10. Drug

    Alemtuzumab

    go.drugbank.com/drugs/DB00087
    ApprovedInvestigational

    [L43397] Alemtuzumab was approved by the FDA in 2001.[L43397] It is marketed as LEMTRADA for multiple sclerosis (MS) treatment and CAMPTAH for B-cell chronic lymphocytic leukemia (B-CLL). … The Campath-1H antibody is an IgG1 kappa with the human variable framework and constant regions, and complementarity-determining regions from a murine (rat) monoclonal antibody (Campath-1G).

    Synonyms: Campath-1H, Campath 1-HProducts: MABCAMPATH INF SOL ICIN 30 MG/ML KONS 1 ML 3 FLK (10 MG/ML KONSANTRE 3 AMP), MABCAMPATH ® 30 MG/ML