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Displaying results 281 - 290 of 10000 in total
  1. Drug

    Naproxen

    go.drugbank.com/drugs/DB00788
    ApprovedInvestigationalVet approved

    [A179098] Naproxen is available in both immediate and delayed release formulations, in combination with sumatriptan to treat migraines, and in combination with esomeprazole to lower the risk of developing … [A178975] It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile.

    Mixtures: TIYOKSEN 550 MG/8 MG FILM TABLET,10 ADET, APRANAX PLUS 550 MG/30 MG FILM KAPLI TABLET, 10 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  2. Drug

    Thiamine

    go.drugbank.com/drugs/DB00152
    ApprovedInvestigationalNutraceuticalVet approved

    It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. … Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi.

    Mixtures: ENJEKSİYONLUK ÇÖZELTİ, 100 AMPUL (50+50), SANASOL 100 ML SURUPProducts: VI-PLEX B1 250 MG/2 ML AMPUL, 100 ADET, VITAMINA B1 (TIAMINA CLORHIDRATO 100 MG./ML)EN FRASCOAMPOLLA POR 10 ML
  3. Drug

    Tetracycline

    go.drugbank.com/drugs/DB00759
    ApprovedInvestigationalVet approvedWithdrawn

    The FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml. … It also binds to some extent to the bacterial 50S ribosomal subunit and may alter the cytoplasmic membrane causing intracellular components to leak from bacterial cells.

    Mixtures: Pylera 140 mg/125 mg/125 mg Hartkapseln, Pylera 140 mg/125 mg/125 mg HartkapselnCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  4. Drug

    Formoterol

    go.drugbank.com/drugs/DB00983
    ApprovedInvestigational

    [L10986] It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers.

    Mixtures: FIXCORT 4.5/160 MG CAPSAIR INHALASYON İÇİN TOZ İÇEREN KAPSÜL, 60 ADET, FIXCORT 4.5/160 MG CAPSAIR INHALASYON İÇİN TOZ İÇEREN KAPSÜL, 120 ADETCategories: Agents to Treat Airway Disease, Cytochrome P-450 Substrates
  5. Drug

    Verapamil

    go.drugbank.com/drugs/DB00661
    ApprovedInvestigational

    [A188514] It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs like [diltiazem] and [flunarizine], but is chemically unrelated to other cardioactive medications … greater potency than the R-enantiomer, but is metabolized at a higher rate.

    Mixtures: VERACOMB MR 180/2 MG KAPSÜL, 28 ADET, VERAPIN 180 MG/2 MG FILM KAPLI TABLET, 28 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  6. Drug

    Triamcinolone

    go.drugbank.com/drugs/DB00620
    ApprovedInvestigationalVet approved

    Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis. … [L8243] In October 2021, a suspension of triamcinolone acetonide was approved for suprachoroidal injection - the first suprachoroidal injection to receive FDA approval[L38973] - for the treatment of patients

    Synonyms: 9α-fluoro-16α-hydroxyprednisolone, 11β,16α,17α,21-tetrahydroxy-9α-fluoro-1,4-pregnadiene-3,20-dioneMixtures: Aureocort 1 mg/g + 30 mg/g Salbe, AFTOJEL % 0,1 + %3 JEL (5 G)
  7. Drug

    Palivizumab

    go.drugbank.com/drugs/DB00110
    ApprovedInvestigational

    Palivizumab is composed of to heavy chains (50.6 kDa each) and two light chains (27.6 kDa each), contains 1-2% carbohydrate by weight and has a molecular weight of 147.7 kDa +/- 1 kDa (MALDI-TOF) … Humanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus (RSV).

    Products: SYNAGIS 50 MG/ML IM ENJEKSIYON ICIN LIYOFILIZE TOZ ICEREN, FLAKON, 1 ADET, SYNAGIS®100 MG SOLUCION PARA INYECCIÓN
  8. Drug

    Dezamizumab

    go.drugbank.com/drugs/DB15153
    Investigational

    Dezamizumab is under investigation in clinical trial NCT03417830 (Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging).

    Synonyms: recombinant monoclonal antibody to human serum amyloid P component
  9. Drug

    Pyridoxine

    go.drugbank.com/drugs/DB00165
    ApprovedInvestigationalNutraceuticalVet approved

    More specifically, pyridoxine is converted to pyridoxal 5-phosphate in the body, which is an important coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids … It's important to note that Vitamin B6 is the collective term for a group of three related compounds, pyridoxine, pyridoxal, and pyridoxamine, and their phosphorylated derivatives, pyridoxine 5'-phosphate

    Mixtures: ISOVIT 100 MG/25 MG TABLET, 500 TABLET, PRİLAM DR 10 MG/10 MG DEĞİŞTİRİLMİŞ SALIMLI TABLET, 30 ADETSynonyms: 5-hydroxy-6-methyl-3,4-pyridinedimethanol
  10. Drug

    Doxorubicin

    go.drugbank.com/drugs/DB00997
    ApprovedInvestigational

    [A257614] Thanks to its efficacy and broad effect, doxorubicin was approved by the FDA in 1974 to treat a variety of cancer, including but not limited to breast, lung, gastric, ovarian, thyroid, non-Hodgkin … [A257709] Although its detailed molecular mechanisms have yet to be understood, doxorubicin is generally thought to exert its effect through DNA intercalation, which eventually leads to DNA damage and

    Synonyms: (1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside, (8S-cis)-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedioneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Inhibitors