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Leucovorin
go.drugbank.com/drugs/DB00650ApprovedInvestigational[L56092, A257419] Unlike folic acid, leucovorin does not require the enzyme dihydrofolate reductase (DHFR) for activation, allowing it to function even when DHFR is inhibited by drugs like methotrexate … [A275451] It is primarily indicated for "leucovorin rescue" to diminish the hematologic and mucosal toxicity of high-dose methotrexate therapy in osteosarcoma and to treat inadvertent overdoses of folic
Mixtures: FERPLEX FOL 40 MG + 0.185 MG/15 ML ORAL ÇÖZELTİ, 10 ADET, KOMFER FOL 40 MG/185 MCG ORAL COZELTI, 10 FLK.Synonyms: 10-Formyl-7,8-dihydrofolic acidBrinzolamide
go.drugbank.com/drugs/DB01194Approved[L35310,L35315] In Europe, it was also approved as a combination product with timolol in 2008.[L35320] … [A2049,A2051] Although systemic anti-carbonic anhydrase (CA) therapy has been used for almost 50 years with varying degrees of success, systemic administration results in an increase in incidences of adverse
Mixtures: AZARGA 10 MG/ML + 5 MG/ML, BRİTİL-T 10 MG/ML + 5 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADETProducts: AZOPT 10 MG/ML ATR, Brinzo-Vision 10 mg/ml AugentropfensuspensionDurvalumab
go.drugbank.com/drugs/DB11714ApprovedInvestigational2020, durvalumab was approved by the FDA for use in combination with [etoposide] and either [carboplatin] or [cisplatin] as first-line treatment of patients with extensive-stage small cell lung cancer (ES-SCLC … It was granted accelerated approval by the FDA in May 2017 [A192807] for the treatment of selected patients with locally advanced or metastatic urothelial carcinoma.
Products: IMFINZI 120 MG/2.4 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET, IMFINZI 500 MG/10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADETTiotropium
go.drugbank.com/drugs/DB01409ApprovedInvestigational[A180163,L7084,L7087,L7090,L7093] Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation. … [A180163] Tiotropium was granted FDA approval on 30 January 2004.[L7084]
Mixtures: FEROMIS 9/12 MCG INHALASYON TOZ ICEREN KAPSUL, 60 ADET, TIOFORM DİSCAİR 18/12 MCG İNHALASYON İÇİN TOZ, 60 DOZProducts: TIODAY CAPSAIR 18 MCG İNHALASYON İÇİN TOZ İÇEREN KAPSÜL, 120 ADET, Braltus 10 Mikrogramm pro abgegebener Dosis Puver zur Inhalation, HartkapselnAcetohydroxamic acid
go.drugbank.com/drugs/DB00551ApprovedInvestigationalIt is used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections. … In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly.
Products: CIPROFLOXACINO 100 MG/10 ML INYECTABLE, CIPROFLOXACINO 100 MG / 10 ML INYECTABLEInfliximab
go.drugbank.com/drugs/DB00065ApprovedInvestigationalIts hyperactivity and enhanced signalling pathways can be observed in inflammatory diseases where it activates further pro-inflammatory cascades. … It is indicated for the treatment of various inflammatory disorders such as adult or pediatric Chron's disease, adult or pediatric ulcerative colitis, rheumatoid arthritis in combination with methotrexate
Synonyms: IMMUNOGLOBULIN G (HUMAN-MOUSE MONOCLONAL CA2 HEAVY CHAIN ANTI-HUMAN TUMOR NECROSIS FACTOR), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL CA2 LIGHT CHAIN, DIMERProducts: REMSIMA SOLUTION FOR SUBCUTANEOUS INJECTION 120 MG/ML IN PRE-FILLED PEN, REMSIMA SOLUTION FOR SUBCUTANEOUS INJECTION 120 MG/ML IN PRE-FILLED SYRINGEDexamethasone
go.drugbank.com/drugs/DB01234ApprovedInvestigationalVet approvedDexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic … [L10701] Developed in 1957, it is structurally similar to other corticosteroids like [hydrocortisone] and [prednisolone].[A188724] Dexamethasone was granted FDA approval on 30 October 1958.
Mixtures: NETILDEX GOZ DAMLASI %0,1 DEKSAMETAZON + %0,3 NETILMISIN 0,3 ML × 20 ADET, TOBRAMICINA E DESAMETASONE EGProducts: TaperDex 12-day, DEKORT 0.75 MG TABLET, 10 TABLETRaltegravir
go.drugbank.com/drugs/DB06817ApprovedInvestigationalIt received approval by the U.S. Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase inhibitors, to receive such approval.
Products: ISENTRESS 400 MG FILM KAPLI TABLET, 60 ADET, Chewable Tablet 100 mgIodide I-123
go.drugbank.com/drugs/DB09420ApprovedInvestigationalRadioactive I-123 in particular is effective for this use as its half-life of approximately 13.13 h (hours) is ideal for the 24-h (hour) iodine uptake test and it has a reduced radiation burden as compared … Iodide I-123 (as sodium Iodide I-123) is a radioactive isotope of iodine used in nuclear medicine for the diagnostic study of thyroid disease.
Synonyms: I 123, I-123Salts: Sodium iodide I-123Domperidone
go.drugbank.com/drugs/DB01184ApprovedInvestigationalVet approvedIt speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Mixtures: DUEDOM 60/10 MG KAPSÜL, 30 ADET, DEXGARD 30/30 MG MR KAPSUL, 60 ADETProducts: DIGESPAR 10 MG, DOMPER TABLET 10 mg