Search
Bupropion
go.drugbank.com/drugs/DB01156ApprovedInvestigational[L6562,A179038,A179050] The combination of naltrexone and bupropion was shown to result in a statistically significant weight loss, with a mean change in body weight of -6.3% compared to -1.3% for placebo … [A178816] Bupropion is sometimes used as an add-on agent to first-line treatments of depression such as selective serotonin reuptake inhibitor (SSRI) medications when there is a treatment-failure or
Categories: Antidepressive Agents Indicated for DepressionProducts: WELLBUTRIN LR, Aplenzin ERAluminum zirconium octachlorohydrex gly
go.drugbank.com/drugs/DB11200ApprovedCurrently, the FDA allows the inclusion of this substance in concentrations of up to 20% in antiperspirants [L2012]. … Interestingly, this chemical has been studied in relation to its possible impact on the microbiome of the human underarms [A32967].
Mixtures: Lactovit DEODORANT ROLL-ON MEN INVISIBLE, Secret Fresh For You Luxe LavenderProducts: Pour Homme Classic Antiperspirant and Deodorant for Men, Secret Clinical Clear Ooh La La LavenderHydroxyproline
go.drugbank.com/drugs/DB08847ApprovedTherapeutically, hydroxyproline is being studied as an an experimental medicine but is approved in France as a combination topical gel product called Cicactive for small, superficial wounds. … Hydroxyproline is a neutral heterocyclic protein amino acid. It is found in collagen and as such it is common in many gelatin products.
Mixtures: Cathycat Chewy CREAM FOUNDATION SPF23 PA WHITENING ANTI WRINKLE 21, Cathycat Chewy CREAM FOUNDATION SPF23 PA WHITENING ANTI WRINKLE 23Synonyms: trans-L-Hydroxyproline, trans-4-Hydroxy-L-prolineCyclobenzaprine
go.drugbank.com/drugs/DB00924ApprovedInvestigationalCyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been available for human use since 1977. … [A184982] It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from [Amitriptyline] by only a single double bond.
Synonyms: N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-Δ5,γ-propylamine, (3-Dibenzo[a,d]cyclohepten-5-ylidene-propyl)-dimethyl-amineProducts: Pro-cyclobenzaprine, Cyclobenzaprine HCL ERCalendula officinalis flower
go.drugbank.com/drugs/DB14263ApprovedCalendula officinalis flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Marigold, Pot, Marigold Pot FlowerBetaine
go.drugbank.com/drugs/DB06756ApprovedInvestigationalNutraceuticalBetaine is a methyl group donor that functions in the normal metabolic cycle of methionine. … It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.
Mixtures: Enl, Pro Gest TabSynonyms: 2-N,N,N-trimethylammonio acetate, N,N,N-TrimethylglycineMethylnaltrexone
go.drugbank.com/drugs/DB06800ApprovedInvestigationalIt is also a weak CYP2D6 inhibitor. FDA approved in 2008. … Methylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation without producing analgesic effects or withdrawal symptoms.
Categories: Drugs for Constipation, Heterocyclic Compounds with 4 or More RingsProducts: RELISTOR (TM) (SUBCUTANEOUS INJECTION,12MG/0.6ML PER VIAL), Relistor Solution For Injection 12mg/0.6mLTedizolid
go.drugbank.com/drugs/DB14569ApprovedInvestigationalThis product is currently available as both an oral tablet and as a powder for intravenous injection.[L11232] … [L11232, A199086, A199050] Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist Pharmaceuticals as tedizolid phosphate (SIVEXTRO®).
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Antibacterials for Systemic UseProducts: SIVEXTRO LYOPHILIZED POWDER FOR SOLUTION FOR INFUSION 200MG PER VIALPOT-4
go.drugbank.com/drugs/DB06056InvestigationalPOT-4 is a peptide that specifically inhibits complement activation and is initially being developed for the treatment of age-related macular degeneration (AMD). … The investigational drug was under investigation in clinical trial NCT00473928 (Safety of Intravitreal POT-4 Therapy for Patients With Neovascular Age-Related Macular Degeneration (AMD) (ASaP)).
Pasireotide
go.drugbank.com/drugs/DB06663ApprovedInvestigationalPasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Synonyms: cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L- phenylalanyl-)International brands: Signifor LAR