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Displaying results 281 - 290 of 495 in total
  1. Drug

    Masitinib

    go.drugbank.com/drugs/DB11526
    InvestigationalVet approved

    It has been available in Europe since 2009, under the brand name Masivet. In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011.

  2. Target

    Cytochrome b-c1 complex subunit 8

    go.drugbank.com/bio_entities/BE0003857
    TargetHumans

    The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.

    Polypeptides: Cytochrome b-c1 complex subunit 8Synonyms: Complex III subunit 8, Complex III subunit VIII
  3. Target

    Cytochrome b-c1 complex subunit 9

    go.drugbank.com/bio_entities/BE0003861
    TargetHumans

    The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.

    Polypeptides: Cytochrome b-c1 complex subunit 9Synonyms: Complex III subunit 9, Complex III subunit X
  4. Target

    Cytochrome b6-f complex subunit 5

    go.drugbank.com/bio_entities/BE0003906
    TargetMastigocladus laminosus

    PetG is required for either the stability or assembly of the cytochrome b6-f complex. … Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.

    Polypeptides: Cytochrome b6-f complex subunit 5Synonyms: Cytochrome b6-f complex subunit V, Cytochrome b6-f complex subunit PetG
  5. Target

    Fatty acid oxidation complex subunit alpha

    go.drugbank.com/bio_entities/BE0004256
    TargetPseudomonas fragi

    Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-Co...

    Polypeptides: Fatty acid oxidation complex subunit alpha
  6. Target

    Trafficking protein particle complex subunit 4

    go.drugbank.com/bio_entities/BE0004278
    TargetHumans

    Core component of the TRAPP complexes which has a function of guanine nucleotide exchange factor activity for Rab1 GTPase (Probable).

    Polypeptides: Trafficking protein particle complex subunit 4
  7. Target

    Trafficking protein particle complex subunit 1

    go.drugbank.com/bio_entities/BE0004279
    TargetHumans

    May play a role in vesicular transport from endoplasmic reticulum to Golgi

    Polypeptides: Trafficking protein particle complex subunit 1
  8. Target

    T-complex protein 1 subunit gamma

    go.drugbank.com/bio_entities/BE0004554
    TargetHumans

    As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638) … Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis (PubMed:25467444, PubMed:36493755

    Polypeptides: T-complex protein 1 subunit gammaSynonyms: Chaperonin containing T-complex polypeptide 1 subunit 3
  9. Target

    T-complex protein 1 subunit eta

    go.drugbank.com/bio_entities/BE0009220
    TargetPlasmodium falciparum (isolate 3D7)

    Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).

    Polypeptides: T-complex protein 1 subunit eta
  10. Target

    H/ACA ribonucleoprotein complex subunit DKC1

    go.drugbank.com/bio_entities/BE0012026
    TargetHumans

    Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA (PubMed:25219674, PubMed:32554502).

    Polypeptides: H/ACA ribonucleoprotein complex subunit DKC1