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Displaying results 281 - 290 of 1809 in total
  1. Drug

    Titanium dioxide

    go.drugbank.com/drugs/DB09536
    Approved

    Titanium dioxide, also known as titanium(IV) oxide or titania, is the naturally occurring oxide of titanium. It is used as a pigment under the names titanium white, Pigment White 6 (PW6), or CI 77891. It is typically extracted from ilmen...

    Mixtures: Vita Water Drop Cc, Skinfood Vita Water Drop CcProducts: Missha M Vita Bb Spf20, Nutritious Vita-mineral Makeup SPF 10
  2. Drug

    Vitamin D

    go.drugbank.com/drugs/DB11094
    ApprovedInvestigationalNutraceuticalVet approved

    Vitamin D ultimately comprises a group of lipid-soluble secosteroids responsible for a variety of biological effects, some of which include increasing the intestinal absorption of calcium, magnesium, and phosphate. With reference to huma...

    Mixtures: Liqui Vita, Vita Plex Tab
  3. Drug

    Mitomycin

    go.drugbank.com/drugs/DB00305
    ApprovedInvestigational

    [A193419] Few other antibiotics have been discovered that work via this alkylating mechanism, making mitomycin relatively unique in the space of microbiota-derived therapies. … [A193419] Mitomycin's cross-linking activity has resulted in its approval for the treatment of a variety of cancers - the most recent of which is an April 2020 approval for its use in low-grade Upper

    Products: MIXANDEX PISA
  4. Target

    Androgen receptor

    go.drugbank.com/bio_entities/BE0000132
    TargetHumans

    activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor

    Polypeptides: Androgen receptorSynonyms: Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4
  5. Target

    Calcitonin receptor

    go.drugbank.com/bio_entities/BE0000431
    TargetHumans

    Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. … CALCR interacts with receptor-activity-modifying proteins RAMP1, 2 and 3 to form receptor complexes AMYR1, 2 and 3, respectively (PubMed:35324283, PubMed:38603770).

    Polypeptides: Calcitonin receptorFunction: amylin receptor activity
  6. Target

    Mineralocorticoid receptor

    go.drugbank.com/bio_entities/BE0000668
    TargetHumans

    Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol.

    Polypeptides: Mineralocorticoid receptorSynonyms: Nuclear receptor subfamily 3 group C member 2
  7. Target

    Oxytocin receptor

    go.drugbank.com/bio_entities/BE0000844
    TargetHumans

    G protein-coupled receptor for oxytocin (OXT), a neuropeptide hormone released by the posterior pituitary gland that plays a key role in social behavior and other biological processes, such as milk ejection … Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as phospholipase C (PubMed

    Polypeptides: Oxytocin receptorFunction: oxytocin receptor activity
  8. Target

    Sigma receptor

    go.drugbank.com/bio_entities/BE0004897
    TargetHumans

    Forms a ternary complex with TMEM97 receptor and low density lipid receptor/LDLR, which increases LDLR-mediated LDL lipoprotein internalization (PubMed:30443021) … Regulates heme synthesis via interactions with FECH and acts as a heme donor for at least some hemoproteins (PubMed:27599036).

    Polypeptides: Sigma non-opioid intracellular receptor 1, Membrane-associated progesterone receptor component 1Synonyms: Sigma1-receptor, Sigma 1-type opioid receptor
  9. Target

    Estrogen receptor

    go.drugbank.com/bio_entities/BE0010245
    TargetHumans

    Nuclear hormone receptor. … Nuclear hormone receptor.

    Polypeptides: Estrogen receptor, Estrogen receptor betaSynonyms: Estradiol receptor, Nuclear receptor subfamily 3 group A member 1
  10. Target

    Somatostatin receptor

    go.drugbank.com/bio_entities/BE0010250
    TargetHumans

    Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. … Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase

    Polypeptides: Somatostatin receptor type 1, Somatostatin receptor type 2Function: G protein-coupled receptor activity