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Radium Ra 223 dichloride
go.drugbank.com/drugs/DB08913ApprovedInvestigationalAs a cation, radium mimics calicum and binds to hydroxyapatite, which is a bone mineral found in areas of high bone turnover as seen in bone metastases. … It was first approved by the FDA in May 2013 and is currently marketed under the brand name Xofigo, which was formerly called Alpharadin.
Linezolid
go.drugbank.com/drugs/DB00601ApprovedInvestigationalLinezolid was initially approved in 2000 and was the first member of the oxazolidinone antibiotic class. … [A233425] A second member of this class, [tedizolid], was approved by the FDA in 2014 and is considered generally more effective and tolerable than its predecessor.
Synonyms: N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamideAminohippuric acid
go.drugbank.com/drugs/DB00345ApprovedInvestigationalWithdrawnThe glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]
Synonyms: N-(p-Aminobenzoyl)glycine, N-(para-aminobenzoyl)glycineCategories: Compounds used in a research, industrial, or household settingIxazomib
go.drugbank.com/drugs/DB09570ApprovedInvestigational[A264319] It was later approved by Health Canada on August 3, 2016,[L51239] and by the EMA on November 21, 2016. … [A264329] Ixazomib was approved by the FDA on November 20, 2015, making it the first oral proteasome inhibitor approved in the US.
Crotalus adamanteus antivenin
go.drugbank.com/drugs/DB13893ApprovedThe majority of people bitten are males and about 50% occur in the age group of 18 to 28 [F116]. … They are large, heavy-bodied snakes with large, broad heads with two light lines on the face [L2877].
Tositumomab
go.drugbank.com/drugs/DB00081ApprovedWithdrawnIt is produced in an antibiotic-free culture of mammalian cells. It can be covalently linked to Iodine 131 (a radioactive isotope of iodine).
Hexocyclium
go.drugbank.com/drugs/DB06787ApprovedHexocyclium is a muscarinic acetylcholine receptor antagonist which was presumably used in the treatment of gastric ulcer or diarrhea. … Proton pump inhibitors like [DB00338] and opiate anti-diarrheal agents like [DB00836] have largely replaced the use of anti-muscarinics in the treatment of gastric ulcers and diarrhea due to their more
L-Acetylleucine
go.drugbank.com/drugs/DB16956ApprovedInvestigationalDL-) form has been available in France since 1957 for the treatment of vertigo. … [A264439] Observational studies in patients with Niemann-Pick disease type C (NPC) suggested a beneficial symptomatic as well as neuroprotective disease-modifying effect of the DL-form of N-acetylleucine
Synonyms: N-acetyl leucine, N-acetylleucineEtonogestrel
go.drugbank.com/drugs/DB00294ApprovedInvestigational[A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.[L5692]
Iodide I-123
go.drugbank.com/drugs/DB09420ApprovedInvestigationalIodide I-123 (as sodium Iodide I-123) is a radioactive isotope of iodine used in nuclear medicine for the diagnostic study of thyroid disease. … Iodine is commonly used in thyroid function diagnostic tests as this gland normally absorbs iodine through the diet for formation of the thyroid hormones triiodothyronine (T3) and its prohormone, thyroxine