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Displaying results 2891 - 2900 of 10000 in total
  1. Drug

    Icosapent

    go.drugbank.com/drugs/DB00159
    ApprovedInvestigationalNutraceutical

    -2 and prostaglandin-2 families. … It serves as the precursor for the prostaglandin-3 and thromboxane-3 families.

    Synonyms: (5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoate, (5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acidMixtures: FERRO SANOL COMP 30 MG/0,5 MG/2,5 MCG KAPSÜL, 30 ADET, GYNOTARDYFERON 80 MG/0,35 MG UZATILMIŞ SALIMLI KAPLI TABLET, 30 ADET
  2. Drug

    Alteplase

    go.drugbank.com/drugs/DB00009
    ApprovedInvestigational

    Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent.[L43125] It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. … [A252330,L43125] Alteplase is a purified glycoprotein of 527 amino acids expressed in Chinese hamster ovary (CHO) cells.

    Mixtures: Activase RT-PA, Lysatec RT - PaSynonyms: t-PA, t-plasminogen activator
  3. Drug

    Levodropropizine

    go.drugbank.com/drugs/DB12472
    Investigational

    Levodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine).

    Mixtures: PULMOTUS 30 MG+ 2 MG/5 ML ŞURUP, 150 ML, DROPOLEV ŞURUP ,150 MLProducts: LEVOPRONT 60 MG TABLET, 20 ADET, LEVOPRONT SYRUP 60 mg/10 ml
  4. Drug

    Maprotiline

    go.drugbank.com/drugs/DB00934
    Approved

    It differs from TCAs in that it does not appear to block serotonin reuptake. … Maprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: MAPROTILIN-NEURAX 50 MG, LUDIOMIL 25 MG TABLET, 60 ADET
  5. Drug

    Thiocolchicoside

    go.drugbank.com/drugs/DB11582
    Investigational

    It is a muscle relaxant with anti-inflammatory and analgesic effects. It has potent convulsant activity and should not be administered to individuals prone to seizures.[L1663] … Thiocolchicoside is a semi-synthetic derivative of the colchicine, a natural anti-inflammatory glycoside which originates from the flower seeds of _Superba gloriosa_.

    Mixtures: LEODEX PLUS 50 MG/8 MG FILM KAPLI TABLET,10 TABLET, LEODEX PLUS 25 MG/8 MG FILM KAPLI TABLET,10 TABLETSynonyms: Thiocolchicine 2-glucoside analog
  6. Drug

    Leuprolide

    go.drugbank.com/drugs/DB00007
    ApprovedInvestigational

    [L13781, L13790] Leuprolide remains frontline therapy in all conditions for which it is indicated for use. … Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH).

    International brands: Prostap 3Products: LUPRON® DEPOT 30 MG, LEUPRONE 5 MG IMPLANT, 1 ADET
  7. Drug

    Interferon beta-1a

    go.drugbank.com/drugs/DB00060
    ApprovedInvestigational

    Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced.

    Synonyms: Interferon beta 1-a, IFN β-1aCategories: interferon beta-1a, Interferon Type I
  8. Drug

    Guanfacine

    go.drugbank.com/drugs/DB01018
    ApprovedInvestigational

    Guanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension[L11274] but is now indicated as an extended release … [A189841] Guanfacine was granted FDA approval on 27 October 1986.[L11274]

    Categories: MATE 1 Inhibitors, Adrenergic alpha-2 Receptor AgonistsProducts: ARİSLOW ER 1 MG UZATILMIŞ SALIMLI TABLET, 28 TABLET, ARİSLOW ER 1 MG UZATILMIŞ SALIMLI TABLET, 7 TABLET
  9. Drug

    Tigozertinib

    go.drugbank.com/drugs/DB19239
    Investigational

    Tigozertinib (BLU-945) is currently under investigation in clinical trial NCT04862780 (Phase 1/​2 Study Targeting EGFR Resistance Mechanisms in NSCLC) for the treatment of NSCLC.

    Synonyms: 3-ISOQUINOLINAMINE, N-(2-((3S,4R)-3-FLUORO-4-METHOXY-1-PIPERIDINYL)-4-PYRIMIDINYL)-5-(1-METHYLETHYL)-8-((2R,3S)-2-METHYL-3-((METHYLSULFONYL)METHYL)-1-AZETIDINYL)-, N-{2-[(3S,4R)-3-fluoro-4-methoxypiperidin-1-yl]pyrimidin-4-yl}-5-(propan-2-yl)-8-[(2R,3S)-2-methyl-3-[(methanesulfonyl)methyl]azetidin-1-yl]isoquinolin-3-amine
  10. Drug

    Tomligisiran

    go.drugbank.com/drugs/DB19330
    Investigational

    B (CHB)). … Tomligisiran is under investigation in clinical trial NCT06537414 (A Study of Sequential Therapy With Daplusiran/tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis

    Synonyms: RNA, ((1'-DE(6-AMINO-9H-PURIN-9-YL))DA-(5'->5')-CM-GM-CM-UM-GM-UM-AM-GM-(2'-DEOXY-2'-FLUORO)G-(2'-DEOXY-2'-FLUORO)C-(2'-DEOXY-2'-FLUORO)A-UM-AM-AM-AM-UM-UM-GM-GM-UM-AM-(3'->3')-SP-(1'-DE(6-AMINO-9H-PURIN, -9-YL))DA), 3'-(O-(CIS-4-((3S,8S)-17-((2-(ACETYLAMI