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Displaying results 2911 - 2920 of 10000 in total
  1. Drug

    Darunavir

    go.drugbank.com/drugs/DB01264
    ApprovedInvestigational

    Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as [ritonavir] for the effective management of HIV-1 infection. … [L9227] Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19, due to in vitro evidence supporting its ability to combat this infection.

    Mixtures: Prezcobix Ped, FURTHAS®R TABLETAS RECUBIERTASCategories: P-glycoprotein inducers, P-glycoprotein inhibitors
  2. Pathway

    Atenolol Action Pathway

    smpdb.ca/view/SMP0000298
    Drug action

    Atenolol, trade name Tenormin, is a beta blocker prescribed to treat hypertension. Atenolol is a selective beta-1-adrenoceptor antagonist targeting the heart and vascular smooth muscle to inhibit sympathetic activity. Binding of atenolol...

    Drugs: ATP · Atenolol · Potassium cation · Calcium
    Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2
  3. Pathway

    Bisoprolol Action Pathway

    smpdb.ca/view/SMP0000300
    Drug action

    Bisoprolol (also known as Zebeta) is a selective beta blocker that can block beta1-adrenergic receptors and beta2-adrenergic receptors. Blocking of beta1-adrenergic receptors in heart and vascular smooth muscle can lead to reduced heart ...

    Drugs: ATP · Bisoprolol · Potassium cation · Calcium
    Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2
  4. Pathway

    Metoprolol Action Pathway

    smpdb.ca/view/SMP0000302
    Drug action

    Metoprolol (also known as Lopressor) is a beta blocker (non-selective) that are used for treat high blood pressure or chest pain. Metoprolol bind to beta1-adrenergic receptors in heart and vascular smooth muscle to block the binding of o...

    Drugs: ATP · Metoprolol · Potassium cation · Calcium
    Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2
  5. Pathway

    Pindolol Action Pathway

    smpdb.ca/view/SMP0000306
    Drug action

    Pindolol (also known as Visken) a beta blocker (non-selective) that block beta-1 adrenergic receptor in heart. Blocking beta-1 adrenergic receptor could prevent the binding of epinephrine and norepinephrine, which could efficiently reduc...

    Drugs: ATP · Pindolol · Potassium cation · Calcium
    Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2
  6. Pathway

    Procainamide (Antiarrhythmic) Action Pathway

    smpdb.ca/view/SMP0000324
    Drug action

    This pathway illustrates the procainamide targets involved in antiarrhythmic therapy. Contractile activity of cardiac myocytes is elicited via action potentials mediated by a number of ion channel proteins. During rest, or diastole, cell...

    Drugs: ATP · Procainamide · Potassium cation · Calcium
    Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2
  7. Pathway

    Fosphenytoin (Antiarrhythmic) Action Pathway

    smpdb.ca/view/SMP0000326
    Drug action

    This pathway illustrates the fosphenytoin targets involved in antiarrhythmic therapy. Contractile activity of cardiac myocytes is elicited via action potentials mediated by a number of ion channel proteins. During rest, or diastole, cell...

    Drugs: ATP · Phenytoin · Fosphenytoin · Potassium cation · Calcium
    Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2
  8. Pathway

    Tocainide Action Pathway

    smpdb.ca/view/SMP0000330
    Drug action

    This pathway illustrates the tocainide targets involved in antiarrhythmic therapy. Contractile activity of cardiac myocytes is elicited via action potentials mediated by a number of ion channel proteins. During rest, or diastole, cells m...

    Drugs: ATP · Tocainide · Potassium cation · Calcium
    Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2
  9. Pathway

    Flecainide Action Pathway

    smpdb.ca/view/SMP0000331
    Drug action

    This pathway illustrates the flecainide targets involved in antiarrhythmic therapy. Contractile activity of cardiac myocytes is elicited via action potentials mediated by a number of ion channel proteins. During rest, or diastole, cells ...

    Drugs: ATP · Flecainide · Potassium cation · Calcium
    Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2
  10. Pathway

    Ibutilide Action Pathway

    smpdb.ca/view/SMP0000332
    Drug action

    This pathway illustrates the ibutilide targets involved in antiarrhythmic therapy. Contractile activity of cardiac myocytes is elicited via action potentials mediated by a number of ion channel proteins. During rest, or diastole, cells m...

    Drugs: ATP · Ibutilide · Potassium cation · Calcium
    Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2