Search
Uric acid
go.drugbank.com/drugs/DB08844InvestigationalUric acid is the last product of purine metabolism in humans. The formation of uric acid is through the enzyme xanthine oxidase, which oxidizes oxypurines. … Normally a small amount of uric acid is present in the body, but when there is an excess amount in the blood, called hyperuricemia, this can lead to gout and formation of kidney stones.
Categories: Compounds used in a research, industrial, or household settingDiphenidol
go.drugbank.com/drugs/DB01231ApprovedWithdrawnDiphenidol is an antiemetic agent used in the treatment of vomiting and vertigo. Diphenidol overdose may result in serious toxicity in children.
COVID19 s-vax loaded autologous dendritic cell vaccine
go.drugbank.com/drugs/DB15814ExperimentalThe rationale is that loading a DC cell with SARS-Cov-2 antigens and administering it as a vaccine can induce a more prolific immune response. … As of May 2020, the company is pursuing a human clinical trial (ChiCTR2000033003) to test the safety and immunogenicity of the vaccine.
Exagamglogene autotemcel
go.drugbank.com/drugs/DB15572ApprovedInvestigational[A262691] Treatment options for SCD are largely focused on preventing the production and circulation of HbS and inducing the production of normal fetal hemoglobin (HbF),[A262696,A262701] including [hydroxyurea … [L10139] Following engraftment, it causes an increase in the production of HbF and a subsequent decrease in HbS.
Synonyms: from mobilised peripheral blood by positive selection, modified by CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9) mediated gene editing consisting ofEstradiol dienanthate
go.drugbank.com/drugs/DB13955ApprovedVet approvedWithdrawnEstradiol is commonly produced with an ester side-chain as endogenous estradiol has very low oral bioavailability on its own (2-10%). … Following absorption, the esters are cleaved, resulting in the release of endogenous estradiol, or 17β-estradiol.
Ambrosia artemisiifolia pollen
go.drugbank.com/drugs/DB10385ApprovedAmbrosia artemisiifolia pollen is the pollen of the Ambrosia artemisiifolia plant. Ambrosia artemisiifolia pollen is mainly used in allergenic testing.
PRO 2000
go.drugbank.com/drugs/DB05385InvestigationalThis medicine does not cure HIV infection or AIDS and is being studied to reduce the risk of passing the virus to other people. … PRO 2000 is an investigational medicine that is not yet approved by the FDA for use outside of clinical trials.
Categories: Compounds used in a research, industrial, or household settingAnifrolumab
go.drugbank.com/drugs/DB11976ApprovedInvestigational[A237054] Anifrolumab has also been investigated for the treatment of Scleroderma.[A237044] Anifrolumab was granted FDA approval on 30 July 2021.[L34929] … [A237054] The design of the clinical trials use different definitions of autoantibody positivity, making comparison between trials difficult; all trials involve large portions of patients also using corticosteroids
Aprocitentan
go.drugbank.com/drugs/DB15059ApprovedInvestigationalAprocitentan is a dual antagonist of endothelin receptors A and B used for treatment-resistant hypertension. It is the active metabolite of [macitentan]. … Approximately 10-15% of patients with hypertension have resistant hypertension, defined as uncontrolled high blood pressure despite the combined use of a renin-angiotensin system blocker, a calcium channel
Golimumab
go.drugbank.com/drugs/DB06674ApprovedInvestigationalulcerative colitis (UC) who require chronic steroids or have experienced intolerance or only a partial response to previous medications. … Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with moderate to severe active rheumatoid arthritis (RA), (ii) alone or as an adjunct to methotrexate
Products: SIMPONI 100MG ILO IN FER, SIMPONI 50MG ILO IN FER