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Displaying results 2931 - 2940 of 10000 in total
  1. Drug

    Elimusertib

    go.drugbank.com/drugs/DB19041
    Investigational

    Elimusertib is under investigation in clinical trial NCT05071209 (Elimusertib for the Treatment of Relapsed or Refractory Solid Tumors).

    Synonyms: 1,7-naphthyridine, 2-((3r)-3-methyl-4-morpholinyl)-4-(1-methyl-1h-pyrazol-5-yl)-8-(1h-pyrazol-3-yl)-Categories: Heterocyclic Compounds, 1-Ring
  2. Drug

    PTX-100

    go.drugbank.com/drugs/DB18125
    Investigational

    Synonyms: 2-{[2-benzyl-4-(5-methyl-3H-imidazol-4-ylmethyl)-3-oxo-piperazine-1-carbonyl]- amino}-4methyl-pentanoic acid
  3. Drug

    Cortisone

    go.drugbank.com/drugs/DB14681
    Investigational

    A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. … It is converted in the liver to the active metabolite hydrocortisone. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)

    Synonyms: 4-pregnene-17α,21-diol-3,11,20-trione, pregn-4-en-17α,21-diol-3,11,20-trioneCategories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 Inducers
  4. Drug

    Cefepime

    go.drugbank.com/drugs/DB01413
    ApprovedInvestigational

    Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. … [A249050] In general, cefepime seems to be well tolerated; however, patients treated with this antibiotic, especially those with renal impairment, may develop neurotoxicity.[A249050,L42095,L42100]

    Categories: Heterocyclic Compounds, 2-RingSynonyms: (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  5. Drug

    Onternabez

    go.drugbank.com/drugs/DB18076
    Experimental

    Synonyms: [(1S,2S,5S)-2-[2,6-dimethoxy-4-(2-methyloctan-2-yl)phenyl]-6,6-dimethyl-4-bicyclo[3.1.1]hept-3-enyl]methanol
  6. Drug

    Dazcapistat

    go.drugbank.com/drugs/DB18301
    Experimental

    Synonyms: N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-4-(2-fluorophenyl)-2-methyloxazole-5-carboxamide, 5-oxazolecarboxamide, n-(3-amino-2,3-dioxo-1-(phenylmethyl)propyl)-4-(2-fluorophenyl)-2-methyl-
  7. Drug

    Cefamandole

    go.drugbank.com/drugs/DB01326
    ApprovedWithdrawn

    It is a parenterally administered broad-spectrum cephalosporin antibiotic. It is generally formulated as a formate ester, [cefamandole nafate]. It is no longer marketed in the United States.

    Synonyms: 7-D-MANDELAMIDO-3-(((1-METHYL-1H-TETRAZOL-5-YL)THIO)METHYL)-3-CEPHEM-4-CARBOXYLIC ACID, 5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, 7-((HYDROXYPHENYLACETYL)AMINO)-3-(((1-METHYL-1H-TETRAZOL-5-YL)THIO)METHYL)-8-OXO-, (6R-(6.ALPHA.,7.BETA.(R*)))-Categories: Heterocyclic Compounds, 2-Ring
  8. Drug

    Apramycin

    go.drugbank.com/drugs/DB04626
    InvestigationalVet approved

    Apramycin is a structurally unique antibiotic that contains a bicyclic sugar moiety and a monosubstituted deoxystreptamine. It is not approved for use in humans. … Apramycin is an aminoglycoside antibiotic and has a bactericidal action against many gram-negative bacteria.

    Synonyms: 4-O-(3α-amino-6α-((4-amino-4-deoxy-α-D-glucopyranosyl)oxy)-2,3,4,5aβ,6,7,8,8aα-octahydro-8β-hydroxy-7β-(methylamino)pyrano(3,2-b)pyran-2α-yl)-2-deoxy-D-streptamine, 4-O-((8R)-2-amino-8-O-(4-amino-4-deoxy-α-D-glucopyranosyl)-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranos-1-yl)-2-deoxy-D-streptamineProducts: TP-APRA 500 WSP ApramycinSulphate 500mg/g Water Soluble Powder, APRAMYCIN 45% ORAL POWDER
  9. Drug

    Vadimezan

    go.drugbank.com/drugs/DB06235
    Investigational

    Synonyms: (5,6-dimethyl-9-oxoxanthen-4-yl)acetic acid, 5,6-Dimethyl-9-oxo-9H-xanthene-4-acetic acidCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 3-Ring
  10. Drug

    Chlorophetanol

    go.drugbank.com/drugs/DB11368
    Experimental

    Chlorophetanol is an agent known to have antifungal activities.

    Synonyms: 2-(4-Chlorophenoxy)ethanol, 2-(4-chlorphenoxy)-ethanolCategories: 2-(4-chlorphenoxy)-ethanol