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Elamipretide
go.drugbank.com/drugs/DB11981ApprovedInvestigational[A274416] This interaction improves mitochondrial morphology and function.[L54036] In September 2025, the U.S. … Food and Drug Administration (FDA) granted accelerated approval for FORZINITY™ (elamipretide) to improve muscle strength in adult and pediatric patients with Barth syndrome weighing at least 30 kg.
Categories: Amino Acids, Peptides, and ProteinsSodium carbonate
go.drugbank.com/drugs/DB09460ApprovedWithdrawnAs a strong base, sodium hydroxide neutralizes gastric acid thereby acting as an antacid. … Sodium Carbonate is the disodium salt of carbonic acid with alkalinizing property. When dissolved in water, sodium carbonate forms carbonic acid and sodium hydroxide.
Gremlin-1
go.drugbank.com/bio_entities/BE0011799TargetHumansCan inhibit the growth or viability of normal cells but not transformed cells when is overexpressed (By similarity) … Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback
Synonyms: Increased in high glucose protein 2, Down-regulated in Mos-transformed cells proteinInavolisib
go.drugbank.com/drugs/DB15275ApprovedInvestigationalInavolisib is an inhibitor of PI3Kα that was approved by the FDA in October 2024 for the treatment of certain patients with advanced breast cancers. … [A264563] Chemotherapeutic agents targeting the PI3K p110α catalytic subunit have shown antitumor activity and a manageable safety profile - some of which are in clinical use, like [alpelisib] - but preclinical
Suvorexant
go.drugbank.com/drugs/DB09034ApprovedInvestigationalSuvorexant is a selective dual antagonist of orexin receptors OX1R and OX2R that promotes sleep by reducing wakefulness and arousal. It has been approved for the treatment of insomnia.
Categories: Hypnotics and Sedatives, Miscellaneous Anxiolytics Sedatives and HypnoticsEtafedrine
go.drugbank.com/drugs/DB11587ApprovedEtafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined with other drugs in the brand names Nethaprin [A32757] and Dalmacol [L2568]. … It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis (now Sanofi) has been discontinued [L2563].
Molybdenum
go.drugbank.com/drugs/DB11137ApprovedInvestigationalIt is an essential trace dietary element and acts as a critical cofactor in several molybdenum-dependent enzymes that are involved in important cellular reactions and pathways, including xanthine oxidoreductase … Molybdenum is commonly used in metallurgy and other chemical applications however it has essential biological roles in organisms and microorganisms.
Mixtures: Spectrum 2 Cap, Iron 25mg With Vit B-cmplx, Vit C, Cu & MoCategories: Diet, Food, and NutritionTetraferric tricitrate decahydrate
go.drugbank.com/drugs/DB14520ApprovedInvestigationalTetraferric tricitrate decahydrate is an iron containing phosphate binder used to treat hyperphosphatemia and iron deficiency anemia in adults with chronic kidney disease. … [A25965] Tetraferric tricitrate decahydrate was granted FDA approval on 5 September 2014.[L9926]
Mixtures: Maxine Vitamin and Mineral SupplementCategories: Drugs for Treatment of Hyperkalemia and HyperphosphatemiaRelacorilant
go.drugbank.com/drugs/DB14976ApprovedInvestigational[L56089] Relacorilant was approved by the US FDA on March 25, 2026, for use in combination with [paclitaxel] in patients with certain platinum-resistant cancers.[L56093,L56089] … Originally investigated to manage the metabolic and endocrinologic complications of hypercortisolism, such as Cushing’s syndrome, its clinical utility has pivoted toward oncology as a potent sensitizing
rhThrombin
go.drugbank.com/drugs/DB04923ApprovedWithdrawnThe production of recombinant proteins is not dependent on the availability of blood from animals or human donors and can be scaled-up to meet market demand. … rhThrombin (recombinant human thrombin) is being developed by ZymoGenetics, Inc. as a general aid to achieving hemostasis during surgery.