Sodium Carbonate is the disodium salt of carbonic acid with alkalinizing property. When dissolved in water, sodium carbonate forms carbonic acid and sodium hydroxide. As a strong base, sodium hydroxide...
- Mechanism
- Curator reviewed
Carbon dioxide from the tissues diffuses rapidly into red blood cells, where it is hydrated with water to form carbonic acid. This reaction is accelerated by carbonic anhydrase, an enzyme present in high concentrations in red blood cells. The carbonic acid formed dissociates into bicarbonate and hydrogen ions. Most of the bicarbonate ions diffuse into the plasma. Since the ratio of H2CO3 to dissolved CO2 is constant at equilibrium, pH may be expressed in terms of bicarbonate ion concentration and partial pressure of CO2 by means of the Henderson-Hasselbach equation: pH = pk + log [HCO3-]/aPCO2
- Primary indication
- Used topically for dermatitides, mouthwash, vaginal douche; veterinary use as emergency emetic.Occasionally, for dermatitides topically as a lotion.Curator reviewed · 1 structured indication
- Formula / weight
- CNa2O3 · 105.9884 g/mol (avg)
- First approval
- Canada, 2017
- Also known as
- Disodium carbonate · Natriumkarbonat · Natrum carbonicum · Soda ash · Soda-ash
- Code names
- E-500(I) · INS-500(I) · INS NO.500(I)
Resolves to
CDBYLPFSWZWCQE-UHFFFAOYSA-LSMILES[Na+].[Na+].[O-]C([O-])=OWhat you can answer from here — as of March 06, 2025
Which drugs share a target with Sodium carbonate, and which of those have an active Phase 3 trial?
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