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Gingerol
go.drugbank.com/drugs/DB19255InvestigationalGingerol is under investigation in clinical trial NCT05882864 (Efficacy of Ginger Muco-bioadhesive Gel in Management of Oral Lichen Planus With Immunohistochemical Analysis).
Synonyms: (5s)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone, (s)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanonePorphobilinogen
go.drugbank.com/drugs/DB02272ExperimentalPorphobilinogen is a pyrrole involved in porphyrin metabolism. It is generated by the enzyme ALA dehydratase, and converted into hydroxymethyl bilane by the enzyme porphobilinogen deaminase.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-(Aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propionic acidAvotaciclib
go.drugbank.com/drugs/DB16652InvestigationalAvotaciclib is under investigation in clinical trial NCT03579836 (Evaluation of Safety and Efficacy in BEY1107 in Monotherapy Gemcitabine Combination in Patient With Pancreatic Cancer).
Synonyms: 2,6-bis(2-aminopyrimidin-4-yl)pyridin-3-olEthotoin
go.drugbank.com/drugs/DB00754ApprovedEthotoin is a hydantoin derivative and anticonvulsant. Ethotoin exerts an antiepileptic effect without causing general central nervous system depression.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersSynonyms: 1-ethyl-2,5-dioxo-4-phenylimidazolidine, (±)-3-ethyl-5-phenylhydantoinZapnometinib
go.drugbank.com/drugs/DB18244InvestigationalSynonyms: Benzoic acid, 2-((2-chloro-4-iodophenyl)amino)-3,4-difluoro-Dasabuvir
go.drugbank.com/drugs/DB09183ApprovedIn a joint recommendation published in 2016, the American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) recommend Dasabuvir as first line therapy … Dasabuvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV).
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: N-{6-[3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl]naphthalen-2-yl}methanesulfonamide, Sodium 3-(3-tert-butyl-4-methoxy-5-{6 [(methylsulfonyl)amino]naphthalene-2-yl}phenyl)-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-ide hydrate (1:1:1)LY-2599506
go.drugbank.com/drugs/DB05970InvestigationalLY2599506 was under investigation in clinical trials NCT01024244 and NCT01029795 for the treatment of patients with type 2 diabetes.
Synonyms: (R)-2-(4-(CYCLOPROPYLSULFONYL)PHENYL)-N-(PYRAZIN-2-YL)-3-(TETRAHYDRO-2H-PYRAN-4-YL)PROPANAMIDE, Gka (R)-1Clopenthixol
go.drugbank.com/drugs/DB13841InvestigationalClopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.
Categories: Heterocyclic Compounds, 3-RingSynonyms: 4-(3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl)-1-piperazineethanol, 4-(3-(2-Chlorothioxanthen-9-ylidene)propyl)-1-piperazineethanolLondamocitinib
go.drugbank.com/drugs/DB19190InvestigationalLondamocitinib is under investigation in clinical trial NCT06020014 (Phase 2a Study to Assess the Efficacy and Safety of AZD4604 in Adult Patients With Moderate-to-severe Asthma Uncontrolled on Medium-high
Synonyms: (R)-N-(3-(5-Fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)pyrimidin-4-yl)-1H-indol-7-yl)-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide, 1-piperazineacetamide, n-(3-(5-fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)-4-pyrimidinyl)-1h-indol-7-yl)-.alpha.-(methoxymethyl)-4-methyl-, (.alpha.r)-SXR-1096
go.drugbank.com/drugs/DB18119InvestigationalSynonyms: 4h-3,1-benzoxazin-4-one, 6-ethoxy-7-methoxy-2-(2-(methylthio)phenyl)-, 6-ethoxy-7-methoxy-2-(2-methylsulfanylphenyl)-3,1-bensoxazin-4-one