Zapnometinib

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Zapnometinib
DrugBank Accession Number
DB18244
Background

Not Available

Type
Small Molecule
Groups
Investigational
Structure
Weight
Average: 409.56
Monoisotopic: 408.91781
Chemical Formula
C13H7ClF2INO2
Synonyms
  • Benzoic acid, 2-((2-chloro-4-iodophenyl)amino)-3,4-difluoro-
External IDs
  • ATR-002
  • PD-0184264

Pharmacology

Indication

Not Available

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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
4RZD8LK83V
CAS number
303175-44-2
InChI Key
XCNBGWKQXRQKSA-UHFFFAOYSA-N
InChI
InChI=1S/C13H7ClF2INO2/c14-8-5-6(17)1-4-10(8)18-12-7(13(19)20)2-3-9(15)11(12)16/h1-5,18H,(H,19,20)
IUPAC Name
2-[(2-chloro-4-iodophenyl)amino]-3,4-difluorobenzoic acid
SMILES
OC(=O)C1=CC=C(F)C(F)=C1NC1=CC=C(I)C=C1Cl

References

General References
Not Available
ChemSpider
8287717
ChEMBL
CHEMBL481949
ZINC
ZINC000022054634

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2TerminatedTreatmentCoronavirus Disease 2019 (COVID‑19)1
1CompletedOtherHealthy Subjects (HS)1
1CompletedTreatmentFlu caused by Influenza1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP6.19Chemaxon
pKa (Strongest Acidic)3.77Chemaxon
pKa (Strongest Basic)-2.5Chemaxon
Physiological Charge-1Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area49.33 Å2Chemaxon
Rotatable Bond Count3Chemaxon
Refractivity80.4 m3·mol-1Chemaxon
Polarizability30.42 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveNoChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at September 15, 2023 14:08 / Updated at September 17, 2023 04:15