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Miravirsen
go.drugbank.com/drugs/DB12851InvestigationalMiravirsen has been investigated for the treatment of Hepatitis C and Hepatitis C, Chronic.
Lefamulin
go.drugbank.com/drugs/DB12825Approved[L8093] This drug is the first semi-synthetic pleuromutilin that has been designed for systemic administration. … A pleuromotilin is a more recently developed type of antibiotic that is derived from the fungus, Pleurotus mutilus.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesAurothioglucose
go.drugbank.com/drugs/DB09121ApprovedWithdrawnMany if not most gold compounds that were indicated for rheumatoid arthritis therapy have since been replaced with the use of various current disease modifying anti-rheumatic drugs (DMARDs) like methotrexate
International brands: Solganal BTriethylenetetramine
go.drugbank.com/drugs/DB06824ApprovedInvestigational[L41730] TETA has been investigated in clinical trials for the treatment of heart failure in patients with diabetes.[A18804,A19332,A19333,A19334,A19335] … Triethylenetatramine (TETA), also known as trientine, is a potent and selective copper (II)-selective chelator. It is a structural analog of linear polyamine compounds, [spermidine] and [spermine].
Categories: Compounds used in a research, industrial, or household settingTelithromycin
go.drugbank.com/drugs/DB00976ApprovedKetolides have been recently added to the macrolide-lincosamide-streptogramin class of antibiotics. … Telithromycin, a semi-synthetic erythromycin derivative, belongs to a new chemical class of antibiotics called ketolides.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: KETEK ® 400 MGIngenol mebutate
go.drugbank.com/drugs/DB05013ApprovedWithdrawnPEP005 is a selective small molecule activator of protein kinase C (PKC) extracted from the plant Euphorbia peplus, whose sap has been used as a traditional medicine for the treatment of skin conditions … Ingenol mebutate was approved by the FDA in January 2012, and it is marketed under the name Picato®. Picato gel is indicated for the topical treatment of actinic keratosis.
Synonyms: 3-Angeloylingenol, 3-Ingenyl angelateVitamin D
go.drugbank.com/drugs/DB11094ApprovedInvestigationalNutraceuticalVet approvedSince vitamin D can be endogenously synthesized in adequate amounts by most mammals exposed to sufficient quantities of sunlight, vitamin D functions like a hormone on vitamin D receptors to regulate calcium … Vitamin D ultimately comprises a group of lipid-soluble secosteroids responsible for a variety of biological effects, some of which include increasing the intestinal absorption of calcium, magnesium, and
Synonyms: D Vitamin, Vitamin DMixtures: GNC Mega Teen, Vitamin E Cream W Vitamins A and DBacitracin
go.drugbank.com/drugs/DB00626ApprovedInvestigationalVet approvedBacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. … [A181952] The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy.
Synonyms: Bacitracin AMixtures: Green Guard Triple Antibiotic, Green Guard Triple AntibioticRiboflavin
go.drugbank.com/drugs/DB00140ApprovedInvestigationalNutraceuticalVet approvedNutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms ...
Synonyms: 6,7-Dimethyl-9-D-ribitylisoalloxazine, 1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitolMixtures: GNC Mega Teen, BLACKMORES teen multi for GUYS capsuleCarbon black
go.drugbank.com/drugs/DB11980Investigational[A263401] Upon inhalation, carbon black has been reported to trigger an inflammatory response in the lung tissue [A263401] and has been linked to carcinogenicity.[A263406, A263411, A263416]
Synonyms: D&C black no. 2, D&C BLACK NO. 2 [II]