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Natural killer cells antigen CD94
go.drugbank.com/bio_entities/BE0010559TargetHumansImmune receptor involved in self-nonself discrimination.
Synonyms: NK cell receptor, Killer cell lectin-like receptor subfamily D member 1Function: HLA-A specific activating MHC class I receptor activityV-type immunoglobulin domain-containing suppressor of T-cell activation
go.drugbank.com/bio_entities/BE0010797TargetHumansImmunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity).
Synonyms: Platelet receptor Gi24, V-set immunoregulatory receptorHuman Amniotic Fluid
go.drugbank.com/drugs/DB15871InvestigationalHuman amniotic fluid is the liquid surrounding the human embryo and fetus. Physically, the fluid provides protection through cushioning. Chemically, the fluid provides protection through its inherent antibacterial properties. The fluid c...
Ethyl pyruvate
go.drugbank.com/drugs/DB05869InvestigationalCTI-01 (ethyl pyruvate) is a novel anti-inflammatory agent for the treatment of critical inflammatory conditions. … CTI-01 shows a potent anti-inflammatory and tissue protection activity in multiple animal models of disease including pancreatitis, ischemia-reperfusion injury, sepsis, renal injury and endotoxemia.
Synonyms: Ethyl 2-oxopropanoate, Ethyl 2-oxopropionateThyroid, porcine
go.drugbank.com/drugs/DB09100ApprovedInvestigational[A190831] Thyroid extract is no longer considered a first line therapy as it delivers a dose that is inconsistent with the stated strength of the tablet. … [A190831,L11755] Thyroid extract has been described in literature to treat hypothyroidism since 1891[A190807] but its use dates back as far as the 6th century.
Haloprogin
go.drugbank.com/drugs/DB00793ApprovedWithdrawnHaloprogin is no longer available in the United States and has been discontinued. … Haloprogin is used as a topical ointment or cream in the treatment of Tinea infections.
Benzthiazide
go.drugbank.com/drugs/DB00562ApprovedThiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood.
Synonyms: 6-chloro-1,1-dioxo-3-(phenylmethylsulfanylmethyl)-4H-benzo[e][1,2,4]thiadiazine-7-sulfonamide, 3-((benzylthio)methyl)-6-chloro-7-sulfamoyl-2H-benzo-1,2,4-thiadiazine 1,1-dioxideCategories: Heterocyclic Compounds, 2-RingTofacitinib
go.drugbank.com/drugs/DB08895ApprovedInvestigationalTofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function. … Besides rheumatoid arthritis, tofacitinib has also been studied in clinical trials for the prevention of organ transplant rejection, and is currently under investigation for the treatment of psoriasis.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: XELJANZ®5MG, เซลแจนซ์ (ยาเม็ด 5 มก.)Metrizoic acid
go.drugbank.com/drugs/DB09346ApprovedMetrizoic acid is a molecule used as a contrast medium. It present a higher risk of allergic reactions due to its high osmolality. Its approval has been discontinued by the FDA. … A total of 10, 000 injections were administered to 2,028 patients undergoing angiocardiographic procedures over a three-year period.
Categories: X-Ray Contrast Activity, X-Ray Contrast Media, IodinatedThymidine
go.drugbank.com/drugs/DB04485ApprovedInvestigational[A274683] While it lacks significant anti-tumor activity on its own,[A274688] it has been extensively investigated for nearly a decade as a biochemical modulator to enhance the efficacy and reduce the … Thymidine is a naturally occurring deoxyribonucleoside that is a crucial component of the DNA salvage pathway and a building block for DNA synthesis.
Synonyms: 1-(2-Deoxy-?-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione, 1-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONECategories: Heterocyclic Compounds, 1-Ring