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Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
go.drugbank.com/bio_entities/BE0003888TargetHumansContributes to calcium sequestration involved in muscular excitation/contraction (PubMed:10914677) … Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen (By similarity).
Polypeptides: Sarcoplasmic/endoplasmic reticulum calcium ATPase 1Synonyms: Calcium pump 1, Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoformVoltage-dependent L-type calcium channel
go.drugbank.com/bio_entities/BE0008715TargetTransporterHumansBeta subunit of voltage-dependent calcium channels which contributes to the function of the calcium channel by increasing peak calcium current (By similarity). … Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents (PubMed:8119293).
Polypeptides: Voltage-dependent L-type calcium channel subunit alpha-1C, Voltage-dependent L-type calcium channel subunit alpha-1DSynonyms: Brain calcium channel I, Voltage-gated calcium channel subunit alpha Cav1.2Voltage-dependent R-type calcium channel
go.drugbank.com/bio_entities/BE0008718TransporterTargetHumansVoltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells (PubMed:30343943). … The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel.
Polypeptides: Voltage-dependent R-type calcium channel subunit alpha-1ESynonyms: Brain calcium channel II, Voltage-gated calcium channel subunit alpha Cav2.3Voltage-dependent N-type calcium channel
go.drugbank.com/bio_entities/BE0009351TargetHumansThe alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel (PubMed:35293990). … The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel.
Polypeptides: Voltage-dependent calcium channel subunit alpha-2/delta-1, Voltage-dependent calcium channel subunit alpha-2/delta-2Synonyms: Brain calcium channel III, Voltage-gated calcium channel subunit alpha-2/delta-1Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
go.drugbank.com/bio_entities/BE0003477TargetTransporterHumansThis magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen (PubMed:12542527, PubMed:16402920).
Polypeptides: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2Synonyms: Calcium pump 2, Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoformVoltage-dependent T-type calcium channel
go.drugbank.com/bio_entities/BE0008716TargetTransporterHumansVoltage-sensitive calcium channel that gives rise to T-type calcium currents. T-type calcium channels belong to the 'low-voltage activated (LVA)' group. … Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone
Polypeptides: Voltage-dependent T-type calcium channel subunit alpha-1G, Voltage-dependent T-type calcium channel subunit alpha-1HSynonyms: Voltage-gated calcium channel subunit alpha Cav3.1, Voltage-gated calcium channel subunit alpha Cav3.2Tumor-associated calcium signal transducer 2
go.drugbank.com/bio_entities/BE0009918TargetHumansMay function as a growth factor receptor
Polypeptides: Tumor-associated calcium signal transducer 2Calcium-activated potassium channel subunit beta-2
go.drugbank.com/bio_entities/BE0003196TargetHumansRegulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.
Polypeptides: Calcium-activated potassium channel subunit beta-2Synonyms: Calcium-activated potassium channel, subfamily M subunit beta-2Calcium-activated potassium channel subunit beta-4
go.drugbank.com/bio_entities/BE0004424TargetHumansMay decrease KCNMA1 channel openings at low calcium concentrations but increases channel openings at high calcium concentrations. … Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.
Polypeptides: Calcium-activated potassium channel subunit beta-4Synonyms: Calcium-activated potassium channel, subfamily M subunit beta-4Calcium/calmodulin-dependent protein kinase kinase 2
go.drugbank.com/bio_entities/BE0009419TargetHumansCalcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes.
Polypeptides: Calcium/calmodulin-dependent protein kinase kinase 2Synonyms: Calcium/calmodulin-dependent protein kinase kinase beta