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Fluconazole
go.drugbank.com/drugs/DB00196ApprovedInvestigationalIt has been demonstrated as an efficacious treatment for vaginal yeast infections in one single dose.[A174325] … It was initially approved by the FDA in 1990. This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole].
Products: DIFLUCAN 100MG, FLUNAZUL 100MGInfliximab
go.drugbank.com/drugs/DB00065ApprovedInvestigationalInfliximab was first approved by the FDA in 1998 under the market name Remicade as an intravenous injection. … Inflectra, a first biosimilar drug product, was approved in 2016. In December 2017, Ixifi, a second biosimilar that was developed by Pfizer, was granted approval by the FDA.
Products: FLIXABI 100MG, REMSIMA 100MGPropranolol
go.drugbank.com/drugs/DB00571ApprovedInvestigational[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.[L6904] … Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors.
Products: OBSIDAN 100MG, Detensol Tab 10mgMorphine
go.drugbank.com/drugs/DB00295ApprovedInvestigationalMorphine was granted FDA approval in 1941.[L12114] … Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805.[A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse.
Synonyms: (7R,7AS,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diolProducts: Bar-morphine SR, CAPROS 100MGMedroxyprogesterone acetate
go.drugbank.com/drugs/DB00603ApprovedInvestigational[L8657,L8660,L8663,L8666,L8669] Medroxyprogesterone acetate was granted FDA approval on 18 June 1959.[L8657]
Products: Provera 100mg Tablets, Provera 10mg TabletsDesipramine
go.drugbank.com/drugs/DB01151ApprovedSecondary amine TCAs, such as desipramine and nortriptyline, are more potent inhibitors of norepinephrine reuptake than tertiary amine TCAs, such as amitriptyline and doxepine. … Desipramine exerts less anticholinergic and sedative side effects compared to tertiary amine TCAs, such as amitriptyline and clomipramine.
Products: Norpramin 100mg Tab, Ratio-desipramine Tab 100mgTramadol
go.drugbank.com/drugs/DB00193ApprovedInvestigational[A4269,A183842] Tramadol has also been shown to affect a number of other pain modulators within the central nervous system as well as non-neuronal inflammatory markers and immune mediators. … Due to its SNRI activity, tramadol also has anxiolytic, antidepressant, and anti-shivering effects which are all frequently found as comorbidities with pain.
Products: T LONG 100MG, TRAMAL 100MGLevetiracetam
go.drugbank.com/drugs/DB01202ApprovedInvestigationalIt was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs).
Products: LEVETIRACETAM BAS 100MG/ML, LEVETIRACETAM GL100 1ML ASOxtriphylline
go.drugbank.com/drugs/DB01303ApprovedAs such, oxytriphylline is indicated mainly for asthma, bronchospasm, and COPD (i.e. all the same indications as the other theophyllines). … Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator.
Products: Rouphylline Tab 100mg, Novo-triphyl Tab 100mgErlotinib
go.drugbank.com/drugs/DB00530ApprovedInvestigationalErlotinib is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase that is used in the treatment of non-small cell lung cancer, pancreatic cancer and several other types of cancer. It is typically marketed under the...
Synonyms: [6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amineProducts: ALVOCEVA FILM-COATED TABLETS 100MG, Tarceva Film Coated Tablet 100mg