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Deferiprone
go.drugbank.com/drugs/DB08826ApprovedInvestigationalDeferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs. Thalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesProducts: FERRIPROX 100 MG/ML SURUP, 500 ML, HİERO 500 MG FİLM KAPLI TABLET, 100 ADETThioridazine
go.drugbank.com/drugs/DB00679ApprovedWithdrawnThioridazine was withdrawn worldwide in 2005 due to its association with cardiac arrythmias. … Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p618).
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin 5-HT2 Receptor AntagonistsSynonyms: 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylsulfanyl-phenothiazine, 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazineQuetiapine
go.drugbank.com/drugs/DB01224ApprovedInvestigationalIt is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such as [clozapine] and [olanzapine].[A2189] … Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin 5-HT1 Receptor AntagonistsProducts: SEQUA 100 MG FILM TABLET, 60 ADET, ETIPIN 100 MG FILM TABLET, 60 ADETCyproterone acetate
go.drugbank.com/drugs/DB04839ApprovedInvestigationalAn anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estroge...
Mixtures: FACETIX®SUAVE 30, DONABELLA® 2 MG /0.035 MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsIrinotecan
go.drugbank.com/drugs/DB00762ApprovedInvestigational[A263376] Approved by the FDA in 1996,[A263366] irinotecan is used to treat colorectal cancer and pancreatic adenocarcinoma. … This leads to the arrest of the cell cycle in the S-G2 phase and cancer cell death.[A263376]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsSynonyms: (S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 4-(2-(5-(3-(2,4-dihydroxy-5-isopropylphenyl)-5-hydroxy-4H-1,2,4-triazol-4-yl)-1H-indol-1-ylZuclopenthixol
go.drugbank.com/drugs/DB01624ApprovedInvestigationalThis compound belongs to the thioxanthenes. … It is known that zuclopenthixol is metabolized by Cytochrome P450 2D6. Zuclopenthixol was approved for use in Canada in 2011, but is not approved for use in the United States.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin 5-HT2 Receptor AntagonistsProducts: CLOPİXOL 10 MG FİLM KAPLI TABLET, 100 ADET, CLOPIXOL 10 MGVildagliptin
go.drugbank.com/drugs/DB04876ApprovedInvestigationalIt is used to manage type II diabetes mellitus, where GLP-1 secretion and insulinotropic effects are impaired. … [A232488] By inhibiting DPP-4, vildagliptin prevents the degradation of glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), which are incretin hormones that promote
Mixtures: VILMET 50 MG/1000 MG FILM KAPLI TABLET ,180 TABLET, GALVUS MET 50/1000 MG FILM KAPLI TABLET, 120 ADETProducts: DIYATIX 50 MG TABLET, 180 ADET, GLIPTA 50 MG TABLET, 180 ADETCarbocisteine
go.drugbank.com/drugs/DB04339ApprovedInvestigationalCarbocisteine is a mucolytic drug that alleviates respiratory symptoms and infections by reducing the viscosity of mucus, allowing it to be expelled. … Individuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of viruses and bacteria in thick bronchial mucus.
Products: MUCOSIS 50 MG/ML ŞURUP, 100 ML, SCMC SYRUP 100 100 mg/5 mlMometasone furoate
go.drugbank.com/drugs/DB14512ApprovedInvestigationalVet approvedMometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label] . It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and highe...
Mixtures: ENERZAIR BREEZHALER INHALATION POWDER, HARD CAPSULE 150 MCG /50 MCG /160 MCG, MORFEX 5/100 MCG INHALASYON IÇIN ÖLÇÜLÜ DOZLU AEROSOL ,120 DOZCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersCalcipotriol
go.drugbank.com/drugs/DB02300ApprovedInvestigationalCalcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.
Mixtures: NuDermRxPAK 120, NuDermRxPAK 120Products: PSORCUTAN % 0.005 MERHEM, 100 G, PSORCUTAN 0,05 MG/ML SCALP ÇÖZELTİ , 60 ML