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Pinaverium
go.drugbank.com/drugs/DB09090ApprovedInvestigationalIt is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function.
Mixtures: DICETEL-DUO, DICETEL® DUOCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTofacitinib
go.drugbank.com/drugs/DB08895ApprovedInvestigationalTofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: XELJANZ® XR 11 MG TABLETAS DE LIBERACIÓN MODIFICADAGlycogen Storage Disease Type II
go.drugbank.com/conditions/DBCOND0002595Synonyms: Glycogen Storage Disease Type II, Glycogen heart diseaseQuinapril
go.drugbank.com/drugs/DB00881ApprovedInvestigationalQuinapril is the ethyl ester prodrug of the non-sulfhydryl angiotensin converting enzyme inhibitor quinaprilat. It is used to treat hypertension and heart failure. ACE inhibitors are commonly used as a first line therapy in the treatment...
Products: ACCUPRIL® TABLETA RECUBIERTA DE 20 MGMycophenolic acid
go.drugbank.com/drugs/DB01024ApprovedInvestigational[A249175] This regimen can be used in place of the older anti-proliferative [azathioprine] due to its stronger immunosuppressive potency. … [A249180,A249185] Mycophenolic acid is available as enteric-coated tablets of delayed-release, in an effort to improve upper gastrointestinal adverse events by delaying mycophenolic acid release until
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesProducts: MICOFENOLATO DE MOFETILO, MICOFENOLATO DE MOFETILO CAPSULAS 250 MGBaclofen
go.drugbank.com/drugs/DB00181ApprovedInvestigationalBaclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasti...
Synonyms: DL-4-Amino-3-p-chlorophenylbutanoic acid, DL-BaclofenInternational brands: Nu-BaclofenLoperamide
go.drugbank.com/drugs/DB00836ApprovedInvestigationalLoperamide is an anti-diarrheal agent that is available as an over-the-counter product for treating diarrhea.[L42785] The drug was first synthesized in 1969 and used medically in 1976. … [A251610] It is a highly lipophilic synthetic phenylpiperidine opioid that works by binding to mu-opioid receptors on intestinal muscles to decrease intestinal motility and electrolyte loss.
Mixtures: Dg Health Anti Diarrheal Anti GasCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesVincristine
go.drugbank.com/drugs/DB00541ApprovedInvestigationalVincristine is an antitumor vinca alkaloid isolated from Vinca Rosea.
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: CITOMID RU ® SOLUCION INYECTABLE, SULFATO DE VINCRISTINA 1 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE.Glipizide
go.drugbank.com/drugs/DB01067ApprovedInvestigationalGlipizide is an oral hypoglycemic agent in the second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 diabetes mellitus.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesSynonyms: 1-cyclohexyl-3-({p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl}sulfonyl)ureaAmiodarone
go.drugbank.com/drugs/DB01118ApprovedInvestigationalAmiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpat...
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: AMIODARONE PH&T, Nu-amiodarone