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Nepafenac
go.drugbank.com/drugs/DB06802ApprovedInvestigationalNepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop. It is used to treat pain and inflammation associated with cataract surgery.
Synonyms: 2-amino-3-benzoylbenzeneacetamideCategories: Selective Cyclooxygenase 2 Inhibitors (NSAIDs)Sulfapyridine
go.drugbank.com/drugs/DB00891ApprovedWithdrawnAntibacterial, potentially toxic, and previously used to treat certain skin diseases. No longer prescribed.
Synonyms: 4-(2-Pyridinylsulfonyl)aniline, 4-Amino-N,2-pyridinylbenzenesulfonamideCategories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsMezlocillin
go.drugbank.com/drugs/DB00948ApprovedSemisynthetic ampicillin-derived acylureido penicillin. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections.
Synonyms: (2S,5R,6R)-3,3-dimethyl-6-{[(2R)-2-({[3-(methylsulfonyl)-2-oxoimidazolidin-1-yl]carbonyl}amino)-2-phenylacetyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6β-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}penicillanic acidCategories: Penicillin G, Heterocyclic Compounds, 2-RingEnasidenib
go.drugbank.com/drugs/DB13874ApprovedInvestigationalFood and Drug Administration on August 1, 2017. … gene, which is a recurrent mutation detected in 12-20% of adult patients with AML [A20344, A20345].
Synonyms: 2-Methyl-1-(4-(6-(trifluoromethyl)pyridin-2-yl)-6-(2-(trifluoromethyl)pyridin-4-ylamino)-1,3,5-triazin-2-ylamino)propan-2-olCategories: Isocitrate Dehydrogenase 2 Inhibitor, Isocitrate dehydrogenase-2 (IDH2) InhibitorsBortezomib
go.drugbank.com/drugs/DB00188ApprovedInvestigationalBortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma. … [A204083] The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: [(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid, [(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic AcidChlorothymol
go.drugbank.com/drugs/DB19375ApprovedChlorotymol is a [Thymol] derivative.
Synonyms: 4-chlor-2-isopropyl-5-methylphenol, 4-chloro-5-methyl-2-(1-methylethyl)phenolBosentan
go.drugbank.com/drugs/DB00559ApprovedInvestigationalBosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals.
Mixtures: OCUBRAX® SUSPENSION OFTALMICA, OCUBRAX® SUSPENSION OFTALMICACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InducersGemcitabine
go.drugbank.com/drugs/DB00441ApprovedInvestigationalGemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers. … [A233135] Gemcitabine is a cytidine analog with two fluorine atoms replacing the hydroxyl on the ribose.
Synonyms: 4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one, 2'-Deoxy-2',2'-difluorocytidineCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein substratesCefmenoxime
go.drugbank.com/drugs/DB00267ApprovedIt is reported to exhibit high activity against a wide variety of gram-positive and gram-negative bacteria. … Cefmenoxime is a novel broad-spectrum and third-generation cephalosporin antibiotic that is typically used in the treatment of female gynecologic and obstetric infections.
Synonyms: (6R,7R)-7-((Z)-2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-((1-methyl-1H-5-tetraazolylthio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure, (6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acidCategories: Heterocyclic Compounds, 2-RingAcrivastine
go.drugbank.com/drugs/DB09488ApprovedAcrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever. … Acrivastine is currently available in combination with pseudoephedrine as the FDA-approved product Semprex-D.
Synonyms: (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}acrylic acidMixtures: DUACT 8 MG/60 MG KAPSÜL, 30 ADET, Semprex-D