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Displaying results 291 - 300 of 10000 in total
  1. Drug

    Deucravacitinib

    go.drugbank.com/drugs/DB16650
    ApprovedInvestigational

    [L43150] It was later approved by Health Canada in November 2022 [L44216] and by the European Medicines Agency in March 2023.[L45788] … [A246943] Deucravacitinib was first approved by the FDA in September 2022 to treat moderate-to-severe plaque psoriasis.

    Products: SOTYKTU® 6MG TABLETAS RECUBIERTAS, SOTYKTU 6 mg film coated tablets
  2. Drug

    Everolimus

    go.drugbank.com/drugs/DB01590
    ApprovedInvestigational

    It is currently used as an immunosuppressant to prevent rejection of organ transplants. … In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and not on the mTORC2 protein.

    Products: EVEROLIMUS EG, Afinitor 3mg Dispersible Tablet
  3. Drug

    Lisinopril

    go.drugbank.com/drugs/DB00722
    ApprovedInvestigational

    [A184781,A184808,A184817] ACEIs are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. … [A184853] It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.

    Mixtures: LISAM 10 mg/5 mg Tabletten, LisAm 20 mg/5 mg TablettenCategories: Agents Acting on the Renin-Angiotensin System, Compounds used in a research, industrial, or household setting
  4. Drug

    Lercanidipine

    go.drugbank.com/drugs/DB00528
    ApprovedInvestigationalWithdrawn

    It is sold under various commercial names including Zanidip.

    Mixtures: ZANITEK 10 MG/10MG FILM TABLET,90 ADET, ZANITEK 10 MG/10MG FILM TABLET, 30 ADETProducts: LERCANIDIPINA EG, CARMEN 10MG
  5. Drug

    Methylprednisolone

    go.drugbank.com/drugs/DB00959
    ApprovedInvestigationalVet approved

    [A188811] It was first described in the literature in the late 1950s.[A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. … [L10785] In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with long-term immunosuppression.

    Mixtures: Physicians EZ Use M-pred, Physicians EZ Use M-predCategories: Compounds used in a research, industrial, or household setting
  6. Drug

    Loratadine

    go.drugbank.com/drugs/DB00455
    ApprovedInvestigational

    [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.

    Mixtures: LORATADINA 5MG/FENILEFRINA 15MG TABLETAS, LARITOL EXProducts: LORATADINA EG, SAFETIN FT
  7. Pathway

    Acylcarnitine (5Z)-7-[(1R,2E,5S)-5-hydroxy-2-[(2E)-oct-2-en-1-ylidene]-3-oxocyclopentyl]hept-5-enoylcarnitine

    smpdb.ca/view/SMP0123485
    Metabolic

    -2-en-1-ylidene]-3-oxocyclopentyl]hept-5-enoylcarnitine. … inner membrane to once again form (5Z)-7-[(1R,2E,5S)-5-hydroxy-2-[(2E)-oct-2-en-1-ylidene]-3-oxocyclopentyl]hept-5-enoyl-CoA and L-carnitine. (5Z)-7-[(1R,2E,5S)-5-hydroxy-2-[(2E)-oct-2-en-1-ylidene]-3

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  8. Drug

    Valproic acid

    go.drugbank.com/drugs/DB00313
    ApprovedInvestigational

    [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. … It first received approval on February 28, 1978 from the FDA under the trade name Depakene.[L6190] Since then, it has been investigated for neuroprotective, anti-manic, and anti-migraine effects.

    Mixtures: Depakine Chronosphere 50 mg Retardgranulat in Beuteln, Depakine Chronosphere 50 mg Retardgranulat in BeutelnSynonyms: 2-n-propyl-n-valeric acid, n-DPA
  9. Drug

    Penciclovir

    go.drugbank.com/drugs/DB00299
    Approved

    Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.

    Products: EX-LOVIR % 1 KREM 2 G, Fenivir - Fieberblasencreme 10mg/g Creme
  10. Drug

    Panobinostat

    go.drugbank.com/drugs/DB06603
    ApprovedInvestigational

    Panobinostat acts as a non-selective histone deacetylase inhibitor (pan-HDAC inhibitor) and it is the most potent DAC inhibiting agent available on the market. … Panobinostat is an oral deacetylace (DAC) inhibitor approved on February 23, 2015 by the FDA for the treatment of multiple myeloma.

    Synonyms: (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide, 2-PROPENAMIDE, N-HYDROXY-3-(4-(((2-(2-METHYL-1H-INDOL-3-YL)ETHYL)AMINO)METHYL)PHENYL)-, (2E)-Products: FARYDAK HARD GELATIN CAPSULE 10mg, FARYDAK HARD GELATIN CAPSULE 15mg