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Bacampicillin
go.drugbank.com/drugs/DB01602ApprovedWithdrawnDuring absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. … Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration.
Synonyms: 1-[(ethoxycarbonyl)oxy]ethyl (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate, 1'-ethoxycarbonyloxyethyl-(6-D-α-aminophenylacetamido)penicillanateCategories: Penicillin G, Heterocyclic Compounds, 2-RingAsenapine
go.drugbank.com/drugs/DB06216ApprovedInvestigationalIt is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use. FDA approved on August 13, 2009. … Developed by Schering-Plough after its merger with Organon International, asenapine is a sublingually administered, atypical antipsychotic for treatment of schizophrenia and acute mania associated with
Categories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsProducts: SYCREST 5MG DILALTI TABLET, TABLET, 20 ADET, SYCREST 10MG DILALTI TABLET, TABLET, 20 ADETTrastuzumab emtansine
go.drugbank.com/drugs/DB05773ApprovedInvestigationalTrastuzumab emtansine, formerly called Trastuzumab-DM1 (T-DM1) is a first-in-class HER2 antibody drug conjugate (ADC) comprised of Genentech's trastuzumab antibody linked to ImmunoGen's cell-killing agent … Trastuzumab emtansine is marketed under the brand name Kadcyla and is indicated for use in HER2-positive, metastatic breast cancer patients who have already used taxane and/or trastuzumab for metastatic
Categories: HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: T-DM1Betula pendula tar oil
go.drugbank.com/drugs/DB11361ApprovedNutraceuticalThe origin plant, also known as the European white or silver birch, grows mainly in the northern hemisphere. … Betula pendula tar oil is an essential oil found in the buds of the plant with the same name.
Synonyms: European white birch tar oilFedratinib
go.drugbank.com/drugs/DB12500ApprovedInvestigationalFedratinib, also known as SAR302503 and TG101348, is a tyrosine kinase inhibitor used to treat intermediate-2 and high risk primary and secondary myelofibrosis. … [A183176,L8090] It is an anilinopyrimidine derivative.[A183188] Fedratinib was granted FDA approval on August 16, 2019.[L8090]
Categories: MATE 2 Inhibitors, MATE 1 InhibitorsProducts: Inrebic 100 mg capsules, Inrebic 100 mg Sert Kapsül, 120 ADETPralidoxime
go.drugbank.com/drugs/DB00733ApprovedInvestigationalVet approvedPralidoxime is an antidote to organophosphate pesticides and chemicals. … If given within 24 hours,after organophosphate exposure, pralidoxime reactivates the enzyme cholinesterase by cleaving the phosphate-ester bond formed between the organophosphate and acetylcholinesterase
Categories: Compounds used in a research, industrial, or household settingSynonyms: 2-PAMPentosan polysulfate
go.drugbank.com/drugs/DB00686ApprovedInvestigationalPentosan polysulfate is a sulfated pentosyl polysaccharide with heparin-like properties.
Synonyms: (4-O-METHYL-.ALPHA.-D-GLUCURONO)-(1->2)-(1->4)-.BETA.-D-XYLOPYRANAN, HYDROGEN SULFATE, (4-O-METHYL-.ALPHA.-D-GLUCURONO)-(1->2)-(1->4)-.BETA.-D-XYLOPYRANAN, HYDROGEN SULPHATEProducts: ELMIRON 100 MG KAPSÜL, 100 ADET, Elmidam 100 mg Sert Kapsül, 100 ADETLomustine
go.drugbank.com/drugs/DB01206ApprovedInvestigationalAn alkylating agent of value against both hematologic malignancies and solid tumors.
Synonyms: N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea, 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosoureaCategories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 CYP3A InhibitorsAngelica archangelica root
go.drugbank.com/drugs/DB14283ApprovedAngelica archangelica root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: European Angelica RootProducts: Park no suk a clear walk of parkCardiolipin Biosynthesis CL(10:0/10:0/13:0/25:0)
smpdb.ca/view/SMP0175386MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...