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Displaying results 3001 - 3010 of 10000 in total
  1. Drug

    Aminacrine

    go.drugbank.com/drugs/DB11561
    Investigational

    A highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with DNA. It is also used as an intracellular pH indicator.

    Categories: Compounds used in a research, industrial, or household setting
  2. Drug

    Saccharin

    go.drugbank.com/drugs/DB12418
    Investigational

    Saccharin has been investigated for the treatment of Hypertension and Hyperglycemia.

    Mixtures: ENO FRUIT SALT (LEMON FLAVOURED)(AUSTRALIA)Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Vayarin

    go.drugbank.com/drugs/DB09328
    Approved

    Vayarin is a novel therapy for ADHD that appears to be effective in several studies [L1501, L1502, L1503]. … Vayarin is currently available only by prescription in the USA [L1502]. This drug has also been used for management of hypertriglyceridemia [L1503].

  4. Drug

    Trilostane

    go.drugbank.com/drugs/DB01108
    ApprovedVet approvedWithdrawn

    Trilostane is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome. It was withdrawn from the United States market in April 1994.

  5. Drug

    Crisaborole

    go.drugbank.com/drugs/DB05219
    ApprovedInvestigational

    This non-steroidal agent is efficacious in improving disease severity, reducing the risk of infection and reducing the signs and symptoms in patients 2 years old and older. … It reduces the local inflammation in the skin and prevents further exacerbation of the disease with a good safety profile.

  6. Drug

    Prostaglandin D2

    go.drugbank.com/drugs/DB02056
    Experimental

    The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, ...

    Synonyms: Prostaglandin D2Categories: Prostaglandins D, Prostaglandin D2, antagonists & inhibitors
  7. Drug

    Cyclophosphamide

    go.drugbank.com/drugs/DB00531
    ApprovedInvestigational

    Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. … It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep.

    Synonyms: N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
  8. Drug

    Rintodestrant

    go.drugbank.com/drugs/DB21472
    Investigational

    Rintodestrant has a monoisotopic molecular weight of 462.09 Da. … Rintodestrant is under investigation in clinical trial NCT03455270 (G1T48, an Oral SERD, Alone and in Combination With Palbociclib in ER-Positive, HER2-Negative Advanced Breast Cancer).

  9. Drug

    Omaveloxolone

    go.drugbank.com/drugs/DB12513
    ApprovedInvestigational

    [L45424] The EMA approved this drug the following year, in February 2024, and Health Canada in March 2025 for the same condition. … [A257529] In February 2023, omaveloxolone was approved by the FDA for the treatment of Friedreich's ataxia in adults and adolescents aged 16 years and older.

    Synonyms: Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro-
  10. Drug

    Dyclonine

    go.drugbank.com/drugs/DB00645
    ApprovedInvestigational

    Dyclonine is an oral anaesthetic found in Sucrets, an over the counter throat lozenge. It may also be found in some Cepacol sore throat spray products.

    Synonyms: 4-n-butoxy-β-(1-piperidyl)propiophenone