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Exenatide
go.drugbank.com/drugs/DB01276ApprovedInvestigationalIt activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control[L42690]. … It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand name product of extended-release exenatide in an injectable suspension, was discontinued in 2021.
Products: BYDUREON® BCISE® 2MG SUSPENSIÓN DE LIBERACIÓN PROLONGADA, BYDUREON 2 mg powder and solvent for prolonged-release suspension for injectionLifitegrast
go.drugbank.com/drugs/DB11611ApprovedInvestigationalIt is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist that was discovered through the rational design process. … It has shown to protect the corneal surface and alleviate the symptoms of dry eye syndrome with fast onset of action and well tolerated profile in both local and systemic setting [A18805].
Lincomycin
go.drugbank.com/drugs/DB01627ApprovedInvestigationalVet approvedLincomycin is a lincosamide antibiotic first isolated from the soil bacterium Streptomyces lincolnensis in Lincoln, Nebraska. Clinical use of lincomycin has largely been superseded by its semisynthetic derivative clindamycin due to its h...
Products: LİNKOMİSİN 500 MG KAPSÜL, LINKOMED 600 MG 1 AMPULDicoumarol
go.drugbank.com/drugs/DB00266ApprovedIn addition to its clinical use, it is also used in biochemical experiments as an inhibitor of reductases.
Pentostatin
go.drugbank.com/drugs/DB00552ApprovedInvestigationalIt is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
Products: CIPROFLOXACINO TABLETAS RECUBIERTAS 500 MG.Mivacurium
go.drugbank.com/drugs/DB01226ApprovedWithdrawnIt binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a block of neuromuscular transmission.
Products: MIVACRON INJECTION 10 mg/5 ml, Mivacron 2 mg/ml - InjektionslösungEpoprostenol
go.drugbank.com/drugs/DB01240ApprovedInvestigationalIt is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension.
Products: VELETRI® 1.5 MG, VELETRI®0.5 MGMP4
go.drugbank.com/drugs/DB05313InvestigationalIt is free of harmful vasoactivity and provides targeted oxygen delivery to tissues at risk of oxygen deprivation.
Medifoxamine
go.drugbank.com/drugs/DB13219ApprovedMedifoxamine was marketed as an atypical antidepressant, with anxiolyitc properties in France, Spain, and Morrocco in the 1990s but was later withdrawn from the market due to it causing cases of hepatotoxicity