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Rociletinib
go.drugbank.com/drugs/DB11907InvestigationalRociletinib has been used in trials studying the treatment and prevention of Nonsmall Cell Lung Cancer, Non-small Cell Lung Cancer, and Locally Advanced or Metastatic Non-small Cell Lung Cancer.
Categories: Heterocyclic Compounds, 1-RingLebrikizumab
go.drugbank.com/drugs/DB11914ApprovedInvestigationalThis approval is based on the positive results obtained from the Phase 3 studies ADvocate 1 and ADvocate 2, where nearly 80% of patients taking lebrikizumab either as monotherapy or combination therapy … Lebrikizumab is a monoclonal antibody that binds to IL-13 with high affinity and slow off-rate.[L51374] It binds to a different epitope compared [tralokinumab].
Indium In-111
go.drugbank.com/drugs/DB11916InvestigationalIndium In-111 is under investigation in clinical trial NCT00493454 (Ibritumomab Tiuxetan for Treatment of Non-Follicular CD20+ Indolent Lymphomas).
Guadecitabine
go.drugbank.com/drugs/DB11918InvestigationalGuadecitabine is under investigation for the treatment of Previously Treated Metastatic Colorectal Cancer.
Categories: Heterocyclic Compounds, 1-Ring6-O-benzylguanine
go.drugbank.com/drugs/DB11919Investigational6-O-benzylguanine has been used in trials studying the treatment of HIV Infection, Adult Gliosarcoma, Adult Glioblastoma, Stage I Adult Hodgkin Lymphoma, and Stage II Adult Hodgkin Lymphoma, among others
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: O(6)-BenzylguanineLesogaberan
go.drugbank.com/drugs/DB11920InvestigationalLesogaberan has been used in trials studying the treatment and basic science of GERD, Reflux, Heartburn, Regurgitation, and Reflux Disease, among others.
Categories: GABA-A Receptor AgonistsEpelsiban
go.drugbank.com/drugs/DB11934InvestigationalEpelsiban has been investigated for the treatment of Premature Ejaculation.
Categories: Heterocyclic Compounds, 1-RingFlomoxef
go.drugbank.com/drugs/DB11935InvestigationalFlomoxef has been used in trials studying the treatment of Urinary Tract Infection.
Categories: Heterocyclic Compounds, 2-RingTriapine
go.drugbank.com/drugs/DB11940InvestigationalTriapine has been used in trials studying the treatment of Leukemia, Lung Cancer, Kidney Cancer, Prostate Cancer, and Pancreatic Cancer, among others.
Synonyms: 3-Aminopyridine-2-carboxaldehyde thiosemicarbazoneCategories: Heterocyclic Compounds, 1-RingSelinexor
go.drugbank.com/drugs/DB11942ApprovedInvestigationalSelinexor is a first-in-class selective inhibitor of nuclear transport (SINE) compound. … Selinexor, in combination with [bortezomib] and [dexamethasone], is currently approved for the treatment of multiple myeloma, a type of cancer formed from antibody-producing plasma cells.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Nexpovio 20 mg Film Kaplı Tablet, 8 TABLET