Triapine

DB11940InvestigationalSmall molecule

Triapine has been used in trials studying the treatment of Leukemia, Lung Cancer, Kidney Cancer, Prostate Cancer, and Pancreatic Cancer, among others.

Chemical structure of Triapine
Formula / weight
C7H9N5S · 195.24 g/mol (avg)
Also known as
3-Aminopyridine-2-carboxaldehyde thiosemicarbazone
Code names
3-AP · NSC-663249 · OCX-0191 · OCX-191 · PAN-811

Resolves to

Compound
UNIIU4XIL4091CCAS143621-35-6ChEMBLCHEMBL231616PubChem9571836
Clinical / RWD
PharmGKBPA165858618
Structure
InChIKeyXMYKNCNAZKMVQN-NYYWCZLTSA-NSMILESNC(=S)N\N=C\C1=C(N)C=CC=N1
Targets
P31350RRM2

What you can answer from here — as of March 19, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
27Clinical trialsPhase, status and sponsor resolved per trial
Sign in
3+ReferencesStructured and connected to the statements they support
Sign in

Which drugs share a target with Triapine, and which of those have an active Phase 3 trial?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In