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Displaying results 3071 - 3080 of 10000 in total
  1. Drug

    Lumefantrine

    go.drugbank.com/drugs/DB06708
    ApprovedInvestigational

    </i> and may be used to treat infections caused by <i>P. falciparum</i> and unidentified <i>Plasmodium</i> species, including infections acquired in chloroquine-resistant areas. … This combination therapy exerts its effects against the erythrocytic stages of <i>Plasmodium spp.

    Mixtures: ARTELERIA (ARTEMETERO 20 MG Y LUMEFANTRINA 120 MG), COARTEM ® 20/120 MG COMPRIMIDOSCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Inhibitors
  2. Drug

    Pemafibrate

    go.drugbank.com/drugs/DB15212
    Investigational

    Pemafibrate is under investigation in clinical trial NCT03350165 (A Study of Pemafibrate in Patients With Nonalcoholic Fatty Liver Disease (NAFLD)).

    Synonyms: K-877Categories: Heterocyclic Compounds, 2-Ring
  3. Drug

    Hymecromone

    go.drugbank.com/drugs/DB07118
    Investigational

    Synonyms: 4-methylumbelliferoneCategories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-Ring
  4. Drug

    Lorcaserin

    go.drugbank.com/drugs/DB04871
    ApprovedInvestigationalWithdrawn

    In February 2020, the FDA issued a Drug Safety Communication requesting the manufacturer of Belviq (lorcaserin hydrochloride tablets, 10 mg) and Belviq XR (lorcaserin hydrochloride extended-release tablets … , 20 mg) to voluntarily withdraw these products from the U.S. market, and the company has submitted a request to voluntarily withdraw the drug.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring
  5. Indication

    Recurrent Miscarriages

    go.drugbank.com/conditions/DBCOND0032265
    Drugs: Dydrogesterone
    Synonyms: Investigation or care in a nonpregnant woman with history of recurrent pregnancy loss
  6. Drug

    Valine

    go.drugbank.com/drugs/DB00161
    ApprovedInvestigationalNutraceutical

    Valine is a branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.

    Synonyms: L-valin, L-valineMixtures: AA-Ven, AMINOMIX 2 NOVUM 2000 ML
  7. Drug

    Pentobarbital

    go.drugbank.com/drugs/DB00312
    ApprovedVet approved

    A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. … It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 InducersSynonyms: 5-Ethyl-5-(1-methyl-butyl)-pyrimidine-2,4,6-trione, 5-ethyl-5-(1-methylbutyl)barbituric acid
  8. Drug

    Padimate O

    go.drugbank.com/drugs/DB11570
    Approved

    It is a structurally-related compound to [DB02362] that absorbs UV-B rays to prevent photodamage. … Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA [L2153].

    Synonyms: Padimate O, Padimate-OMixtures: Vichy-lait Solaire SPF 10, Kiss My Face SPF 18 Lip Balm
  9. Drug

    Butorphanol

    go.drugbank.com/drugs/DB00611
    ApprovedIllicitVet approved

    A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.

    Synonyms: (−)-N-cyclobutylmethyl-3,14-dihydroxymorphinanCategories: Heterocyclic Compounds with 4 or More Rings
  10. Drug

    Methoxyflurane

    go.drugbank.com/drugs/DB01028
    ApprovedInvestigationalVet approvedWithdrawn

    If so employed, it should be administered with nitrous oxide to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular … An inhalation anesthetic. Currently, methoxyflurane is rarely used for surgical, obstetric, or dental anesthesia.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: Penthrop 99,9%, 3 ml Flüssigkeit zur Herstellung eines Dampfs zur Inhalation, PENTHROX®