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Displaying results 301 - 310 of 10000 in total
  1. Target

    NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

    go.drugbank.com/bio_entities/BE0000493
    TargetHumans

    Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:30879903, PubMed:3155...

    Polypeptides: NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
  2. Target

    Heat shock protein 75 kDa, mitochondrial

    go.drugbank.com/bio_entities/BE0014134
    TargetHumans

    Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the bala...

    Polypeptides: Heat shock protein 75 kDa, mitochondrialSynonyms: HSP 75
  3. Drug

    European pilchard

    go.drugbank.com/drugs/DB10622
    Approved

    European pilchard allergenic extract is used in allergenic testing.

    Synonyms: European pilchard
  4. Drug

    Pyrantel

    go.drugbank.com/drugs/DB11156
    ApprovedVet approved

    Pyrantel is on the World Health Organization's List of Essential Medicines, which are the safest and most effective medicines required in a functioning health system [L1901], [L1902]. … Pyrantel is mainly available in formulations for dogs and cats as the embonate salt, containing a 34.7% pyrantel base [L1900].

    Mixtures: Heartgard Plus Chewable Tablet for Dogs - Up to 25 lbs, PAMOATO DE OXANTEL 250 MG/5ML + PAMOATO DE PIRANTEL 250 MG/5 ML SUSPENSIÓN.Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Latanoprost

    go.drugbank.com/drugs/DB00654
    ApprovedInvestigational

    Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998. … Another benefit latanoprost is that it can be administered once a day.[A184490]

    Mixtures: Latanoprost comp ratiopharm 50 Mikrogramm/ml und 5 mg/ml Augentropfen, LATANOPROST 0.05 MG/ML AND TIMOLOL 5 MG/ML SANDOZ EYE DROPSCategories: Compounds used in a research, industrial, or household setting, Prostaglandins F, Synthetic
  6. Drug

    Isradipine

    go.drugbank.com/drugs/DB00270
    Approved

    It exhibits greater selectivity towards arterial smooth muscle cells owing to alternative splicing of the alpha-1 subunit of the channel and increased prevalence of inactive channels in smooth muscle cells

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: DYNACIRC SRO 5 MG, DYNACIRC COMPRIMIDOS 2.5 MG
  7. Drug

    Guaifenesin

    go.drugbank.com/drugs/DB00874
    ApprovedInvestigationalVet approved

    to be safe and effective in children under the age of 6 years [F4525]. … Guaifenesin possesses a storied history, having been originally formally approved by the US FDA in 1952 and continues to be one of very few - if not perhaps the only drug that is readily available and

    International brands: Duratuss GMixtures: BROKSIN 6.66 MG/5 ML+100 MG/5 ML SURUP, 150 ML, BİCANA 1,5 MG/5 ML + 66,5 MG/5 ML ŞURUP, 100 ML
  8. Drug

    Citalopram

    go.drugbank.com/drugs/DB00215
    ApprovedInvestigational

    It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs. … [A261316,A14720] Specifically, it has a very minimal effect on dopamine and norepinephrine transportation and virtually no affinity for muscarinic, histaminergic, or GABAergic receptors.

    Categories: Serotonin 5-HT2 Receptor Antagonists, P-glycoprotein inhibitorsProducts: CITREX 40 MG/ML 15 ML ORAL DAMLA, M-citalopram
  9. Drug

    Methylergometrine

    go.drugbank.com/drugs/DB00353
    ApprovedInvestigational

    A homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed)

    Synonyms: 9,10-Didehydro-N-[1-(hydroxymethyl)-propyl]-D-lysergamide, D-lysergic acid 1-butanolamideInternational brands: Ingagen-M, Partan M
  10. Drug

    Escitalopram

    go.drugbank.com/drugs/DB01175
    ApprovedInvestigational

    that the R-enantiomer of racemic citalopram actively dampens the activity of escitalopram rather than existing simply as an inactive enantiomer. … Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic [citalopram].

    Synonyms: (S)-Citalopram, S(+)-CitalopramCategories: Heterocyclic Compounds, 2-Ring, P-glycoprotein substrates