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Risperidone
go.drugbank.com/drugs/DB00734ApprovedInvestigational[L12885] Risperidone binds with a very high affinity to 5-HT2A receptors, approximately 10-20 fold greater than the drug's binding affinity to D2 receptors, and carries lesser activity at several off-targets … [L12885] Schizophrenia and various mood disorders are thought to be caused by an excess of dopaminergic D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways
Categories: Dopamine D2 Receptor Antagonists, Cytochrome P-450 SubstratesInternational brands: Risperidal M-TabLosartan
go.drugbank.com/drugs/DB00678ApprovedInvestigational[L7423] Losartan is available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and hydrochlorothiazide. … [L7423] Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough.
Mixtures: CONVERTAL D 100, Ag-losartan HctzCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsAluminum acetate
go.drugbank.com/drugs/DB14518ApprovedInvestigationalProducts: ACETATO DE ALUMINIO 15 MG/100 ML SOLUCION TOPICA, ACETATO DE ALUMINIO 0.118G/100 MLGlycerin
go.drugbank.com/drugs/DB09462ApprovedInvestigationalA trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Synonyms: Monoctanoin component DMixtures: MICROLAX LAVMAN, 10 G, P3 AiHepatitis B immune globulin
go.drugbank.com/drugs/DB05276ApprovedInvestigationalInfection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatitis-B vaccines are cancer-preventing vaccines.
Products: HEPAGAM B 1560 IU/5 ML IM/IV ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ, HEPATECT CP 500 IU 10 ML FLAKONCodeine
go.drugbank.com/drugs/DB00318ApprovedIllicitInvestigationalCodeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory … [A175096] Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic agent, and is also recommended in certain diseases with incessant coughing.
Mixtures: Doladamon P 300 mg/15 mg/10 mg Kaplı Tablet, A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 20 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesAdenosine
go.drugbank.com/drugs/DB00640ApprovedInvestigational[A229828] Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy,[L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole]
Synonyms: beta-D-Adenosine, 9-beta-D-RibofuranosidoadenineMixtures: MU LAB TURN AROUND 2W Refresh Ex, AHC Vital Complex C-15 AmpouleBrinzolamide
go.drugbank.com/drugs/DB01194Approved[A2049,A2051] Although systemic anti-carbonic anhydrase (CA) therapy has been used for almost 50 years with varying degrees of success, systemic administration results in an increase in incidences of adverse … [A2051] Brinzolamide was approved by the FDA in 1998 as a standalone product and in 2013 as a combination product with brimonidine tartrate.
Mixtures: AZARGA 10 MG/ML + 5 MG/ML, SIMBRINZA EYE DROPS, SUSPENSION 10 MG/ML + 2 MG/MLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesSertraline
go.drugbank.com/drugs/DB01104ApprovedInvestigationalSertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine].
Categories: Monoamine Oxidase A Substrates, Cytochrome P-450 SubstratesProducts: Nu-sertraline Capsules, AS-SERTRAL 100 MG FILM TABLET, 14 ADETOrlistat
go.drugbank.com/drugs/DB01083ApprovedInvestigationalIt was approved by the FDA for use in combination with a reduced-calorie diet in 1999. … [A229928] Orlistat is a lipase inhibitor used in the treatment of obesity that works by inhibiting fat-metabolizing enzymes.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersProducts: ORLISTAT 120 MG, FINOBES ® 120 MG.