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Lurasidone
go.drugbank.com/drugs/DB08815ApprovedInvestigationalIt was approved by the U.S.
Categories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT1 Receptor AntagonistsProducts: ESLUX® 80 MG TABLETAS RECUBIERTAS, ESLUX® 40 MG TABLETAS RECUBIERTASTrimetazidine
go.drugbank.com/drugs/DB09069ApprovedInvestigational[A233215] It is hypothesized that trimetazidine inhibits 3-ketoacyl coenzyme A thiolase, which decreases fatty acid oxidation but not glucose metabolism, preventing the acidic conditions that exacerbate … However, it has been approved in France since 1978.[L33020]
Synonyms: 1-[2,3,4-trimethoxybenzyl] piperazine dihydrochlorideInternational brands: Vastarel MRPonatinib
go.drugbank.com/drugs/DB08901ApprovedInvestigationalPonatinib is a novel Bcr-Abl tyrosine kinase inhibitor that is especially effective against the T315I mutation for the treatment of chronic myeloid leukemia. FDA approved on December 14, 2012.
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: ICLUSIG® 15 MG TABLETAS RECUBIERTAS, ICLUSIG TABLET 15 MGChronic hepatitis C genotype 5
go.drugbank.com/conditions/DBCOND0024500Synonyms: Chronic hepatitis C genotype 5Yohimbine
go.drugbank.com/drugs/DB01392ApprovedInvestigationalVet approvedWithdrawnA plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Synonyms: (16α,17α)-17-hydroxyyohimban-16-carboxylic acid methyl esterInternational brands: Baron-XDiphenoxylate
go.drugbank.com/drugs/DB01081ApprovedIllicitInvestigationalWhen diphenoxylate is used alone, it is classified as a Schedule II. … A meperidine congener used as an antidiarrheal, usually in combination with atropine. At high doses, it acts like morphine.
Synonyms: Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotate, 1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-isonipecotic acid ethyl esterMixtures: LOMOTİL 2,5 MG + 0,025 MG / 5 ML ORAL ÇÖZELTİ, 60 ML, LAMDOTIL®Captopril
go.drugbank.com/drugs/DB01197ApprovedInvestigationalCaptopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension.
Synonyms: (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid, D-2-methyl-3-mercaptopropanoyl-L-prolineMixtures: CAPOZIDE 50/25 MG TABLETAS, CAPTOPRIL E IDROCLOROTIAZIDE HEXALFesoterodine
go.drugbank.com/drugs/DB06702ApprovedFesoterodine is an antimuscarinic prodrug for the treatment of overactive bladder syndrome.
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: TOVIAZ 4 MG UZATILMIS SALIMLI TABLET, 14 ADET, TOVIAZ 8 MG UZATILMIS SALIMLI TABLET, 14 ADETTestosterone
go.drugbank.com/drugs/DB00624ApprovedInvestigationalTestosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.
Categories: 3-Oxoandrosten (4) Derivatives, P-glycoprotein inhibitorsSynonyms: 4-androsten-17β-ol-3-one, 17beta-hydroxy-4-androsten-3-oneBaricitinib
go.drugbank.com/drugs/DB11817ApprovedInvestigational[A248405] While baricitinib was granted emergency use as a treatment for COVID-19 in combination with [remdesivir] under the Emergency Use Authorization (EUA) in November 2020,[L22619] the FDA fully approved … the use of baricitinib for the treatment of COVID-19 in May 2022.
Categories: Heterocyclic Compounds, 1-Ring, Experimental Unapproved Treatments for COVID-19Products: UNAMİTY 4 MG FİLM KAPLI TABLET, 14 ADET, UNAMİTY 2 MG FİLM KAPLI TABLET, 14 ADET