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Tenapanor
go.drugbank.com/drugs/DB11761ApprovedInvestigational[L8558] It was first designed and synthesized in 2012. … [A185492] As an inhibitor of the sodium/hydrogen exchanger isoform 3 (NHE3) transporter, it is the first and currently only medication within its class[A185489,A185492,A185495] and therefore exists as
Categories: Alimentary Tract and MetabolismStill's Disease
go.drugbank.com/conditions/DBCOND0066232Drugs: TetracosactideSynonyms: Still disease with juvenile onset and/or adult onset, Still's disease with juvenile onset and/or adult onset (disorder)Tauroursodeoxycholic acid
go.drugbank.com/drugs/DB08834ApprovedInvestigationalWithdrawn[A249070] It is a taurine conjugate of [ursodeoxycholic acid] [A249065] with comparable therapeutic efficacy and safety,[A249070] but a much higher hydrophilicity. … Tauroursodeoxycholic acid can reduce the absorption of cholesterol in the small intestine, thereby reducing the body's intake of dietary cholesterol and the body cholesterol content.
Categories: Bile Acids and Salts, Bile and Liver TherapyTislelizumab
go.drugbank.com/drugs/DB14922ApprovedInvestigational[L49439] Tislelizumab was also approved by the FDA on March 14, 2024.[L50346] It has subsequently been approved for additional cancers in the US and EU. [L49349] … This approval was based on positive results demonstrated in the RATIONALE 302 study, where an 8.6-month median overall survival rate was observed for tislelizumab treatment compared to 6.3-month for chemotherapy
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsAvutometinib
go.drugbank.com/drugs/DB15254ApprovedInvestigational[A273948] Avutometinib was approved by the US FDA in May 2025 in a co-package alongside [defactinib] (called Avmapki Fakzynja) for the treatment of recurrent KRAS-mutated low-grade serous ovarian cancer … [L53203,L53198] The MAPK pathway is implicated in variety of cancers, playing a key role in tumor cell proliferation, differentiation and survival.
Synonyms: N-(3-fluoro-4-((4-methyl-2-oxo-7-((pyrimidin-2-yl)oxy)-2H-1-benzopyran-3-yl)methyl)pyridin-2-yl)-N'-methylsulfuric diamide, Sulfamide, N-(3-fluoro-4-((4-methyl-2-oxo-7-(2-pyrimidinyloxy)-2H-1-benzopyran-3-yl)methyl)-2-pyridinyl)-N'-methyl-Procaine benzylpenicillin
go.drugbank.com/drugs/DB09320ApprovedVet approvedProcaine benzylpenicillin is administered by deep intramuscular injection. It is slowly absorbed and hydrolyzed to benzylpenicillin. … Procaine benzylpenicillin (INN), also known as procaine G penicillin, is an injectable antiobiotic.
Mixtures: PENCAIN K-800 İ.Ü. IM ENJEKTABL FLAKON, 1 FLAKON + 1 AMPUL, PENCAIN K-400 İ.Ü. ENJEKTABL FLAKON, 1 FLAKON + 1 AMPULFidaxomicin
go.drugbank.com/drugs/DB08874ApprovedInvestigational[A190501] Because fidaxomicin contains an 18-membered lactone ring in its structure, it is referred to as a macrocyclic lactone antibiotic drug. … Fidaxomicin is a novel macrolide antibiotic used in the treatment of diarrhea caused by _Clostridioides_ (formerly _Clostridium_) _difficile_ in adult and pediatric patients over the age of 6 months.
Categories: Alimentary Tract and MetabolismAngle-Closure Glaucoma
go.drugbank.com/conditions/DBCOND0041713Drugs: PilocarpineSynonyms: Glaucoma, Closed-Angle, Closed-angle glaucomaSelenic acid
go.drugbank.com/drugs/DB11068ApprovedIt may be found in over-the-counter daily dietary supplements as a source of [DB11135], an essential trace mineral for human health. … Selenic acid is an organic compound with the chemical formula H2SeO4.
Mixtures: Balance Ace - Cap, Prenatal and Post Partum SupplementCategories: Compounds used in a research, industrial, or household setting, Diet, Food, and NutritionCultivated mushroom
go.drugbank.com/drugs/DB10544ApprovedCultivated mushroom allergenic extract is used in allergenic testing.
Synonyms: Agaricus bisporus (mushroom) cap/stem extract