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Displaying results 3111 - 3120 of 10000 in total
  1. Target

    Claudin-16

    go.drugbank.com/bio_entities/BE0009861
    TransporterHumans

    In the thick ascending limb (TAL) of Henle's loop, facilitates sodium paracellular permeability from the interstitial compartment to the lumen, contributing to the lumen-positive transepithelial potential

    Polypeptides: Claudin-16
  2. Indication

    Catheter-related Bloodstream Infection

    go.drugbank.com/conditions/DBCOND0037994
    Drugs: Cefazolin · Doripenem · Taurolidine
    Synonyms: Bloodstream infection due to central venous catheter
  3. Drug

    Thyme

    go.drugbank.com/drugs/DB10983
    Approved

    Thyme allergenic extract is used in allergenic testing.

    Mixtures: MENTOSEPTOL GARGARA, 100 ML, BRONCHİPRET ŞURUP, 50 ML
  4. Drug

    CDX-1135

    go.drugbank.com/drugs/DB17607
    Investigational

    CDX-1135, formerly TP-10, is a soluble, recombinant human Complement Receptor Type 1 (sCR1) developed by Avant Immunotherapeutics (now Celldex).

  5. Drug

    Plazomicin

    go.drugbank.com/drugs/DB12615
    Approved

    It mediates the antibacterial activity by binding to bacterial 30S ribosomal subunit and inhibiting protein synthesis [FDA Label]. … Like other aminoglycosides, plazomicin is ineffective against bacterial isolates that produce 16S rRNA methyltransferases [FDA Label].

  6. Drug

    MK-2748

    go.drugbank.com/drugs/DB15371
    Investigational

    MK-2748 is under investigation in clinical trial NCT01593735 (A Multiple Dose Study to Evaluate the Safety and Efficacy of MK-2748 in Hepatitis C-Infected Participants (MK-2748-002 AM1)).

  7. Drug

    Gluconic Acid

    go.drugbank.com/drugs/DB13180
    ApprovedInvestigational

    Gluconic acid or gluconate is used to maintain the cation-anion balance on electrolyte solutions.

    Mixtures: ISOLYTE SISE 500 ML(SETSIZ), ISOLYTE-S PH 7.4 PVC 500 ML(SETLI)
  8. Drug

    Ceftolozane

    go.drugbank.com/drugs/DB09050
    ApprovedInvestigational

    [L6685] It was approved by the FDA in 2014 for use in combination with [Tazobactam] for the treatment of serious infections, such as intra-abdominal infections and complicated urinary tract infections.

    Mixtures: ZERBAXA 1 G/0.5 G INFÜZYONLUK KONSANTRE ÇÖZELTI HAZIRLAMAK IÇIN TOZ IÇEREN FLAKON, 10 FLAKON, ZERBAXA ® 1 G/0.5 GSynonyms: (6R,7R)-3-([3-Amino-4-(2-aminoethylcarbamoylamino)-2-methylpyrazol-1-ium-1-yl]methyl)-7-([(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino)-8-oxo-5-thia-1-azabicyclo[
  9. Drug

    Pectin

    go.drugbank.com/drugs/DB11158
    ApprovedInvestigationalVet approved

    This status allows pectin to be used with no limitations.[L1960]

    Mixtures: MGC Health, MGC Health
  10. Drug

    LI-301

    go.drugbank.com/drugs/DB05509
    Experimental

    It has a novel mode of action combining both the light effect of a Selective Serotonin Reuptake Inhibitor ("SSRI")(most likely antagonistic at 5HT1a receptors) and antagonism at mu-opioid receptors. … LI 301 is an orally bio-available compound delivered in a fast melt mechanism with taste masking enabling it to be taken anytime without water.