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Propylene glycol
go.drugbank.com/drugs/DB01839ApprovedInvestigationalA clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Mixtures: SYSTANE ULTRA (UD) (LUBRICANT EYE DROPS), SK Lubricant Eye DropsCategories: Compounds used in a research, industrial, or household settingMK-1064
go.drugbank.com/drugs/DB15028InvestigationalMK-1064 is under investigation in clinical trial NCT02549014 (A Single Dose Study of the Safety, Pharmacokinetics and Pharmacodynamics of MK-1064 (MK-1064-001)).
MK-6325
go.drugbank.com/drugs/DB15249InvestigationalMK-6325 is under investigation in clinical trial NCT01329913 (Safety, Pharmacokinetics, and Pharmacodynamics of MK-6325 in Hepatitis C Virus (HCV) Infections (MK-6325-003)).
MK-8666
go.drugbank.com/drugs/DB14937InvestigationalMK-8666 is under investigation in clinical trial NCT01971554 (Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of MK-8666 in Participants With Type 2 Diabetes Mellitus (MK-8666-003)).
Tanogitran
go.drugbank.com/drugs/DB21367InvestigationalTanogitran is under investigation in clinical trial NCT02254057 (Tolerability and Pharmacokinetics/-Dynamics of Single Rising Doses BIBT 986 BS in Healthy Male Subjects).
Famtozinameran
go.drugbank.com/drugs/DB17088ApprovedInvestigationalIt is administered in combination with [tozinameran] for active immunization against COVID-19 caused by SARS-CoV-2, including infection caused by Omicron BA.4/BA.5.[L43907,L43912]
Rucaparib
go.drugbank.com/drugs/DB12332ApprovedInvestigationalan androgen receptor–directed therapy, confirming clinical benefit for an indication that previously had accelerated approval. … On December 17, 2025, the FDA granted regular approval to rucaparib for adults with a deleterious BRCA mutation–associated metastatic castration-resistant prostate cancer (mCRPC) previously treated with
Idiopathic Pulmonary Fibrosis (IPF)
go.drugbank.com/conditions/DBCOND0031843Synonyms: Idiopathic pulmonary fibrosis, acute fatal form, Idiopathic fibrosing alveolitis, acute fatal formBiguanide
go.drugbank.com/drugs/DB13100ApprovedInvestigationalWithdrawnBiguanide has been investigated for the treatment of Diabetes Mellitus.
Dihydroergotamine
go.drugbank.com/drugs/DB00320ApprovedInvestigationalDihydroergotamine is used as an abortive therapy for migraines. … Recent improvements have been made in the design of intranasal delivery devices allowing for greater delivery of dihydroergotamine solution to the vasculature-rich upper nasal cavity.
Categories: Heterocyclic Compounds with 4 or More Rings