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Telaprevir
go.drugbank.com/drugs/DB05521ApprovedWithdrawnTelaprevir was available as a fixed dose product (tradename Incivek) used for the treatment of chronic Hepatitis C. … Incivek has since been withdrawn from the market.
Synonyms: (1S,3aR,6aS)-(2S)-2-cyclohexyl-N-(pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-((1S)-1-((cyclopropylamino)oxoacetyl)butyl)octahydrocyclopenta(c)pyrrole-1-carboxamideBMS-582949
go.drugbank.com/drugs/DB12696InvestigationalBMS-582949 has been investigated for the treatment of Psoriasis.
Gadofosveset trisodium
go.drugbank.com/drugs/DB06705ApprovedGadofosveset trisodium is an intravenous contrast agent used with magnetic resonance angiography(MRA), which is a non-invasive way of imaging blood vessels. The agent allows for the vascular system to be imaged more clearly by the MRA. I...
Ifenprodil
go.drugbank.com/drugs/DB08954ApprovedInvestigationalWithdrawn] it has also been shown to have an immunomodulatory effect. … [A220133] Further studies elucidated that ifenprodil binds strongly at the inter-subunit interface of adjacent GluN1 and GluN2B NTDs, where it acts as a non-competitive antagonist.
Vanzacaftor
go.drugbank.com/drugs/DB18373ApprovedInvestigational[L52275,A179677] Vanzacaftor was first approved by the US FDA in December 2024 in combination with another CFTR corrector - [tezacaftor], which binds to a different site than vanzacaftor - and [deutivacaftor
Ephedra sinica root
go.drugbank.com/drugs/DB01363ApprovedNutraceuticalThe sale of ephedra-containing supplements intended to increase muscle weight or promote weight loss was banned in the United States in 2004 due to the risk for adverse effects and a lack of evidence for
Erlotinib
go.drugbank.com/drugs/DB00530ApprovedInvestigationalErlotinib is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase that is used in the treatment of non-small cell lung cancer, pancreatic cancer and several other types of cancer. It is typically marketed under the...
Synonyms: [6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amineTagatose
go.drugbank.com/drugs/DB04936InvestigationalIt is approved as a food additive as a low calorie sweetener. Additionally, it is under investigation by Spherix for the treatment of obesity and type II diabetes.
Clothiapine
go.drugbank.com/drugs/DB13256ApprovedClothiapine has been approved in European countries and is an atypical antipsychotic, shown to be useful in some treatment-resistant patients.
R-30490
go.drugbank.com/drugs/DB09179ExperimentalIt was first synthesized by Janssen Pharmaceutica as part of a structure-activity relationship study of fentanly and its derivatives. … R-30490 is an opioid related to carfentanil used as an animal tranquilizer.