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Displaying results 3131 - 3140 of 10000 in total

Drug
Pyridostigmine
go.drugbank.com/drugs/DB00545
ApprovedInvestigational
[A231009, A231014, L32413, L32418] Pyridostigmine was granted initial FDA approval on April 6, 1955, as an oral tablet. … Myasthenia gravis is an autoimmune disease involving dysfunction at the neuromuscular junction, most commonly due to autoantibodies directed against the acetylcholine receptor (AChR), which results in
International brands: Kalymin N
Drug
Capsicum
go.drugbank.com/drugs/DB10897
Approved
Capsicum (Chili pepper) allergenic extract is used in allergenic testing.
Mixtures: C Ottways Lax Tab, Salonpas pain relieving HOT-L
Drug
Albiglutide
go.drugbank.com/drugs/DB09043
ApprovedInvestigationalWithdrawn
It is a dipeptidyl peptidase-4-resistant glucagon-like peptide-1 dimer fused to human albumin. Albiglutide was approved on April 15, 2014 by the FDA. … Albiglutide is a glucagon-like peptide-1 agonist (GLP-1) biologic drug indicated in the treatment of type 2 diabetes. It is marketed under the brands Eperzan and Tanzeum by GSK (GlaxoSmithKline).
Categories: Drugs Used in Diabetes
Drug
Brentuximab vedotin
go.drugbank.com/drugs/DB08870
ApprovedInvestigational
Importantly, bleomycin - a highly toxic agent - was completely removed from the regimen. This demonstrates meaningful progress in treatment for patients affected by this disease.[L1739] … Food and Drug Administration approved Adcetris in March 2018 to treat adult patients with previously untreated stage III or IV classical Hodgkin lymphoma (cHL) in combination with chemotherapy.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: ADCETRIS 50 MG (POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION), POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 50MG/VIAL
Drug
GC-376 free acid
go.drugbank.com/drugs/DB15796
Experimental
GC-376 is a 3C-like protease (3CLpro or Mpro) inhibitor that stops the cleavage and activation of functional viral proteins required for replication and transcription in host cells … In addition, GC-376 displays potent activity against various coronaviruses such as feline, ferret, and mink Mpro coronavirus[A219026,A219031,A219036,A219041].
Categories: Experimental Unapproved Treatments for COVID-19
Drug
Dydrogesterone
go.drugbank.com/drugs/DB00378
ApprovedInvestigationalWithdrawn
A synthetic progestational hormone with no androgenic or estrogenic properties. … Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.
Drug
Dimazole
go.drugbank.com/drugs/DB13858
ApprovedWithdrawn
Dimazole (diamthazole) is an antifungal. It was withdrawn in Franch in 1972 due to neuropsychiatric reactions.
Categories: Antifungals for Topical Use, Antifungals for Dermatological Use
Indication
Vision Disorders
go.drugbank.com/conditions/DBCOND0035879
Drugs: Almitrine · Faricimab · Ranibizumab
Synonyms: Poor vision
Drug
EVT 302
go.drugbank.com/drugs/DB06057
Investigational
EVT 302 is an orally active, potent, highly selective and reversible inhibitor of MAO-B. It is in the development for smoking cessation, and potential for disease modification in Alzheimer's disease.
Drug
ANA971
go.drugbank.com/drugs/DB05127
Experimental
ANA971, an orally administered prodrug of isatoribine. Isatoribine is a nucleoside analog in development for the treatment of chronic hepatitis C virus (HCV) infection. … ANA971 is a prodrug designed to improve the oral bioavailability of isatoribine.