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Basiliximab
go.drugbank.com/drugs/DB00074ApprovedInvestigationalA recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also … known as CD25 antigen) on the surface of activated T-lymphocytes.
Categories: Interleukin-2 Receptor Antagonist, Interleukin-2 Receptor Blocking AntibodyProducts: SIMULECT® LIOFILIZADO PARA INYECCION 20 MG/VIAL, SIMULECT 20 MG İNFÜZYON VEYA ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 1 ADETPentoxyverine
go.drugbank.com/drugs/DB11186ApprovedWithdrawnPentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors. The FDA withdrew the use of all oral gel drug products containing pentoxyverine citrate. … It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and H1-receptor antagonists [A32160].
Mixtures: GAYABEN 150 ML SURUP, V-cofProducts: PENTOXYVERIN AL 1.35 MG/ML, Mucomat Hustenstiller 2,13 mg/ml Lösung zum EinnehmenDPDPE
go.drugbank.com/drugs/DB08861ExperimentalA heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond.
Synonyms: L-tyrosyl-3-mercapto-D-valylglycyl-L-phenylalanyl-3-mercapto-D-valine, cyclic (2-5)-disulfide, (D-Pen2,D-Pen5)-EnkephalinAlpelisib
go.drugbank.com/drugs/DB12015ApprovedInvestigationalAlpelisib was designed to target this enzyme that appears to be mutated at a rate of nearly 30% in human cancers, leading to hyperactivation. … It works by selectively inhibiting class I PI3K p110α [A179203], which is the catalytic subunit of PI3K, a lipid kinase that plays a role in various biological processes, including proliferation, survival
Categories: Heterocyclic Compounds, 1-Ring, Class I Phosphatidylinositol 3-Kinases, antagonists & inhibitorsProducts: PİMREVA 200 MG FİLM KAPLI TABLET, 14 ADET, PİMREVA 200 MG FİLM KAPLI TABLET, 28 ADETTafamidis
go.drugbank.com/drugs/DB11644ApprovedInvestigational[A189717] Tafamidis was granted an EMA market authorisation on 16 November 2011[L6247] and FDA approval on 3 May 2019.[L11280]
Categories: Heterocyclic Compounds, 2-RingSynonyms: 2-(3,5-Dichlorophenyl)benzoxazole-6-carboxylic acid, 6-BENZOXAZOLECARBOXYLIC ACID, 2-(3,5-DICHLOROPHENYL)-Pentazocine
go.drugbank.com/drugs/DB00652ApprovedVet approvedIt is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Categories: P-glycoprotein substratesProducts: Pentazocine-Fresenius 30 mg/ml injection, Talwin - Liq 30mg/mlCysteamine
go.drugbank.com/drugs/DB00847ApprovedInvestigationalCystinosis is a rare disease caused by mutations in the CTNS gene that encodes for cystinosin, a protein responsible for transporting cystine out of the cell lysosome. … [L15606] Cysteamine eye drops are a practical and effective option for those affected by ocular cystinosis.
Synonyms: 2-amino-1-ethanethiol, 2-aminoethanethiolProducts: CYSTAGON ® 50 MG CAPSULAS, CYSTAGON ® 150 MGMoclobemide
go.drugbank.com/drugs/DB01171ApprovedInvestigationalA reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder.
Categories: Cytochrome P-450 Substrates, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesSynonyms: 4-Chlor-N-(2-morpholinoethyl)benzamid, p-Chloro-N-(2-morpholinoethyl)benzamideSevelamer
go.drugbank.com/drugs/DB00658ApprovedInvestigationalSevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Categories: Compounds used in a research, industrial, or household settingProducts: RENVELA 2,4 G ORAL SÜSPANSIYON IÇIN TOZ, 60 SAŞE, RENVELA 2,4 G ORAL SÜSPANSIYON IÇIN TOZ, 90 SAŞESufentanil
go.drugbank.com/drugs/DB00708ApprovedInvestigational(AcelRx), was approved on November 2, 2018 [L4717]. … It is administered by the intravenous, epidural and sublingual routes.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesSynonyms: N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilide, N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-N-phenylpropanamide